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GeneE
0 sources retrieved Β· Most recent: April 2026 Β· Index updated 15 days ago
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ARL13A
ARF like GTPase 13A
Chromosome X Β· Xq22.1
NCBI Gene: 392509Ensembl: ENSG00000174225.15HGNC: HGNC:31709UniProt: Q5H913
5PubMed Papers
8Diseases
0Drugs
0Pathogenic Variants
DATA QUALITY
βœ“ Experimental GO Evidenceβœ“ Swiss-Prot Reviewed
ciliary membranenon-motile ciliumreceptor localization to non-motile ciliumnon-motile cilium assemblyNeurodevelopmental disorderciliopathyImmunodeficiencyJoubert syndrome
✦AI Summary

AI summary not yet available. Showing NCBI Gene summary.

ARF like GTPase 13A

⚠Limited data available β€” This gene has 0 indexed publications. Summary and analysis may be incomplete.
Disease Associationsβ“˜8
Neurodevelopmental disorderOpen Targets
0.12Weak
ciliopathyOpen Targets
0.01Suggestive
ImmunodeficiencyOpen Targets
0.00Suggestive
Joubert syndromeOpen Targets
0.00Suggestive
lung carcinomaOpen Targets
0.00Suggestive
esophageal cancerOpen Targets
0.00Suggestive
nonpapillary renal cell carcinomaOpen Targets
0.00Suggestive
thyroid cancer, nonmedullary, 1Open Targets
0.00Suggestive
Pathogenic Variants
No pathogenic variants reported on ClinVar for this gene.
View on ClinVar β†—
Related Genes
TMEM80Shared pathway100%TBCDProtein interaction74%RPGRIP1Shared pathway50%GORABShared pathway50%CC2D2BShared pathway50%C2CD3Shared pathway33%
Tissue Expression6 tissues
Bone Marrow
100%
Ovary
75%
Lung
33%
Liver
25%
Brain
19%
Heart
0%
Gene Interaction Network
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ARL13ATMEM80TBCDRPGRIP1GORABCC2D2BC2CD3
PROTEIN STRUCTURE
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AlphaFoldAI-predicted Β· UniProt Q5H913
View on AlphaFold β†—
Constraintβ“˜
LOEUFβ“˜
1.27LoF Tolerant
pLIβ“˜
0.00Tolerant
Observed/Expected LoF0.84 [0.57–1.27]
RankingsWhere ARL13A stands among ~20K protein-coding genes
  • #18,287of 20,598
    Most Researched5
  • #13,436of 17,882
    Most Constrained (LOEUF)1.27
Genes detectedARL13A
Sources retrieved0 papers
Response timeβ€”