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GeneE
0 sources retrieved Β· Most recent: April 2026 Β· Index updated 14 days ago
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C15orf62
chromosome 15 open reading frame 62
Chromosome 15 Β· 15q15.1
NCBI Gene: 643338Ensembl: ENSG00000188277.10HGNC: HGNC:34489UniProt: A8K5M9
10PubMed Papers
8Diseases
0Drugs
0Pathogenic Variants
DATA QUALITY
βœ“ Experimental GO Evidenceβœ“ Swiss-Prot Reviewed
mitochondrionRho protein signal transductionregulation of cell shapepositive regulation of actin filament polymerizationbenign neoplasm of eyeesophageal adenocarcinomaBarrett's esophagusesophageal squamous cell carcinoma
✦AI Summary

AI summary not yet available. Showing NCBI Gene summary.

chromosome 15 open reading frame 62

⚠Limited data available β€” This gene has 0 indexed publications. Summary and analysis may be incomplete.
Disease Associationsβ“˜8
benign neoplasm of eyeOpen Targets
0.06Suggestive
esophageal adenocarcinomaOpen Targets
0.03Suggestive
Barrett's esophagusOpen Targets
0.03Suggestive
esophageal squamous cell carcinomaOpen Targets
0.03Suggestive
lower respiratory tract diseaseOpen Targets
0.02Suggestive
oral squamous cell carcinomaOpen Targets
0.01Suggestive
dysplasiaOpen Targets
0.01Suggestive
spina bifidaOpen Targets
0.00Suggestive
Pathogenic Variants
No pathogenic variants reported on ClinVar for this gene.
View on ClinVar β†—
Related Genes
CDC42EP3Shared pathway100%CDC42EP4Shared pathway100%CDC42EP5Shared pathway100%CDC42EP1Shared pathway80%CDC42EP2Shared pathway57%PALM2AKAP2Shared pathway25%
Tissue Expression6 tissues
Liver
100%
Bone Marrow
71%
Ovary
70%
Lung
52%
Heart
20%
Brain
17%
Gene Interaction Network
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C15orf62CDC42EP3CDC42EP4CDC42EP5CDC42EP1CDC42EP2PALM2AKAP2
PROTEIN STRUCTURE
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AlphaFoldAI-predicted Β· UniProt A8K5M9
View on AlphaFold β†—
Constraintβ“˜
LOEUFβ“˜
1.37LoF Tolerant
pLIβ“˜
0.00Tolerant
Observed/Expected LoF0.83 [0.52–1.37]
RankingsWhere C15orf62 stands among ~20K protein-coding genes
  • #17,002of 20,598
    Most Researched10
  • #14,289of 17,882
    Most Constrained (LOEUF)1.37
Genes detectedC15orf62
Sources retrieved0 papers
Response timeβ€”