C15orf62 — chromosome 15 open reading frame 62

5 sources retrieved · Most recent: April 2026 · Index updated 3 months ago

10PubMed Papers

#17,220 · top 89% of 19K genes

8Diseases

top 95%

0Drugs

0Pathogenic Variants

Experimental GO EvidenceSwiss-Prot Reviewed

mitochondrionRho protein signal transductionregulation of cell shapepositive regulation of actin filament polymerizationbenign neoplasm of eyeesophageal adenocarcinomaBarrett's esophagusesophageal squamous cell carcinoma

AI Summary

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chromosome 15 open reading frame 62

⚠Limited data available — This gene has 0 indexed publications. Summary and analysis may be incomplete.

Disease Associations8

benign neoplasm of eyeOpen Targets

0.06Suggestive

esophageal adenocarcinomaOpen Targets

0.03Suggestive

Barrett's esophagusOpen Targets

0.03Suggestive

esophageal squamous cell carcinomaOpen Targets

0.03Suggestive

lower respiratory tract diseaseOpen Targets

0.02Suggestive

oral squamous cell carcinomaOpen Targets

0.01Suggestive

dysplasiaOpen Targets

0.01Suggestive

spina bifidaOpen Targets

0.00Suggestive

Pathogenic Variants

No pathogenic variants reported on ClinVar for this gene.

Tissue Expression6 tissues

Liver

100%

Bone Marrow

71%

Ovary

70%

Lung

52%

Heart

20%

Brain

17%

Gene Interaction Network6 neighbors

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StructureAlphaFold

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AlphaFoldAI-predicted · UniProt A8K5M9

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ConstraintgnomAD v4.1

LOEUFⓘ

1.37LoF Tolerant

pLIⓘ

0.00Tolerant

Observed/Expected LoF0.83 [0.52–1.37]

Rankings2 dim

Where C15orf62 stands among ~20K protein-coding genes

#17,002of 20,598
Most Researched10
#14,289of 17,882
Most Constrained (LOEUF)1.37