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GeneE
0 sources retrieved Β· Most recent: April 2026 Β· Index updated 15 days ago
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CFAP141
cilia and flagella associated protein 141
Chromosome 1 Β· 1q21.3
NCBI Gene: 388701Ensembl: ENSG00000163263.7HGNC: HGNC:32305UniProt: Q5VU69
9PubMed Papers
9Diseases
0Drugs
0Pathogenic Variants
DATA QUALITY
βœ“ Experimental GO Evidenceβœ“ Swiss-Prot Reviewed
protein bindingaxonemal microtubulesperm flagellumaxonemal A tubule inner sheathprostate carcinomasmoking initiationsubstance abuselower respiratory tract disease
✦AI Summary

AI summary not yet available. Showing NCBI Gene summary.

cilia and flagella associated protein 141

⚠Limited data available β€” This gene has 0 indexed publications. Summary and analysis may be incomplete.
Disease Associationsβ“˜9
prostate carcinomaOpen Targets
0.07Suggestive
smoking initiationOpen Targets
0.03Suggestive
substance abuseOpen Targets
0.02Suggestive
lower respiratory tract diseaseOpen Targets
0.02Suggestive
attention deficit hyperactivity disorderOpen Targets
0.02Suggestive
Chronic Obstructive AsthmaOpen Targets
0.02Suggestive
atrial fibrillationOpen Targets
0.02Suggestive
secondary progressive multiple sclerosisOpen Targets
0.01Suggestive
ovarian serous cystadenocarcinomaOpen Targets
0.00Suggestive
Pathogenic Variants
No pathogenic variants reported on ClinVar for this gene.
View on ClinVar β†—
Related Genes
LRRC23Shared pathway100%RIBC2Shared pathway100%SPAG8Shared pathway100%LZTFL1Shared pathway100%PRM3Shared pathway100%CFAP68Shared pathway100%
Tissue Expression6 tissues
Bone Marrow
100%
Lung
50%
Brain
29%
Liver
17%
Ovary
8%
Heart
0%
Gene Interaction Network
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CFAP141LRRC23RIBC2SPAG8LZTFL1PRM3CFAP68
PROTEIN STRUCTURE
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PDB7UNG Β· 3.60 Γ… Β· EM
View on RCSB β†—
Constraintβ“˜
LOEUFβ“˜
1.30LoF Tolerant
pLIβ“˜
0.00Tolerant
Observed/Expected LoF0.83 [0.55–1.30]
RankingsWhere CFAP141 stands among ~20K protein-coding genes
  • #17,296of 20,598
    Most Researched9
  • #13,687of 17,882
    Most Constrained (LOEUF)1.30
Genes detectedCFAP141
Sources retrieved0 papers
Response timeβ€”