CFAP184 is a cilia and flagella-associated protein that functions as a regulatory component of ciliary beating machinery. Based on limited published evidence, CFAP184 acts in complex with CFAP263 to connect radial spoke 3 (RS3) to the inner dynein arm (IDA) and nexin-dynein regulatory complex (N-DRC), positioning itself parallel to N-DRC at the arch base of RS3. The protein localizes to axonemes and ciliary basal bodies and is involved in cilium assembly. A recent transcriptomic study identified CFAP184 as a potential downstream target in the ZFP36-GBP6 signaling pathway 1, though the functional relevance to mitral valve biology requires further investigation.