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GeneE
0 sources retrieved Β· Most recent: April 2026 Β· Index updated 14 days ago
β“˜GeneE is for informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment.
CFAP263
cilia and flagella associated protein 263
Chromosome 16 Β· 16q21
NCBI Gene: 29070Ensembl: ENSG00000103021.11HGNC: HGNC:25002UniProt: Q9H0I3
26PubMed Papers
20Diseases
0Drugs
0Pathogenic Variants
DATA QUALITY
βœ“ Experimental GO Evidenceβœ“ Swiss-Prot Reviewed
protein-containing complexcilium assemblyciliary basal bodyprotein bindingplacenta praeviasystemic lupus erythematosuscolorectal carcinomaneoplasm
✦AI Summary

AI summary not yet available. Showing NCBI Gene summary.

cilia and flagella associated protein 263

⚠Limited data available β€” This gene has 0 indexed publications. Summary and analysis may be incomplete.
Disease Associationsβ“˜20
placenta praeviaOpen Targets
0.34Weak
systemic lupus erythematosusOpen Targets
0.19Weak
colorectal carcinomaOpen Targets
0.07Suggestive
neoplasmOpen Targets
0.04Suggestive
male infertilityOpen Targets
0.03Suggestive
colorectal cancerOpen Targets
0.02Suggestive
squamous cell carcinomaOpen Targets
0.02Suggestive
nasopharyngeal neoplasmOpen Targets
0.01Suggestive
asthmaOpen Targets
0.01Suggestive
large cell medulloblastomaOpen Targets
0.01Suggestive
chronic interstitial cystitisOpen Targets
0.01Suggestive
infertilityOpen Targets
0.01Suggestive
cancerOpen Targets
0.00Suggestive
lung cancerOpen Targets
0.00Suggestive
colonic neoplasmOpen Targets
0.00Suggestive
chronic obstructive pulmonary diseaseOpen Targets
0.00Suggestive
primary ciliary dyskinesiaOpen Targets
0.00Suggestive
Alzheimer diseaseOpen Targets
0.00Suggestive
oligoasthenoteratozoospermiaOpen Targets
0.00Suggestive
chronic rhinosinusitisOpen Targets
0.00Suggestive
Pathogenic Variants
No pathogenic variants reported on ClinVar for this gene.
View on ClinVar β†—
Related Genes
CIBAR2Shared pathway100%CFAP184Shared pathway100%HYLS1Shared pathway100%LRRC45Shared pathway100%WDR90Shared pathway100%PTPDC1Shared pathway100%
Tissue Expression6 tissues
Brain
100%
Heart
76%
Ovary
21%
Liver
20%
Lung
18%
Bone Marrow
6%
Gene Interaction Network
Click a node to explore
CFAP263CIBAR2CFAP184HYLS1LRRC45WDR90PTPDC1
PROTEIN STRUCTURE
Preparing viewer…
PDB8J07 Β· 4.10 Γ… Β· EM
View on RCSB β†—
Constraintβ“˜
LOEUFβ“˜
1.61LoF Tolerant
pLIβ“˜
0.00Tolerant
Observed/Expected LoF1.23 [0.95–1.61]
RankingsWhere CFAP263 stands among ~20K protein-coding genes
  • #12,754of 20,598
    Most Researched26
  • #15,719of 17,882
    Most Constrained (LOEUF)1.61
Genes detectedCFAP263
Sources retrieved0 papers
Response timeβ€”