ELAPOR2 — endosome-lysosome associated apoptosis and autophagy regulator family member 2

5 sources retrieved · Most recent: April 2026 · Index updated 3 months ago

14PubMed Papers

#16,004 · top 82% of 19K genes

20Diseases

top 81%

0Drugs

0Pathogenic Variants

Experimental GO EvidenceSwiss-Prot Reviewed

protein bindingBMP receptor bindingpositive regulation of BMP signaling pathwaypositive regulation of epidermis developmentresponse to stimuluschronic fatigue syndromegeneralized dystoniathyroiditis

AI Summary

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endosome-lysosome associated apoptosis and autophagy regulator family member 2

⚠Limited data available — This gene has 0 indexed publications. Summary and analysis may be incomplete.

Disease Associations20

response to stimulusOpen Targets

0.33Weak

chronic fatigue syndromeOpen Targets

0.28Weak

generalized dystoniaOpen Targets

0.28Weak

thyroiditisOpen Targets

0.28Weak

ACPA-positive rheumatoid arthritisOpen Targets

0.27Weak

cholelithiasisOpen Targets

0.26Weak

aseptic looseningOpen Targets

0.26Weak

revision of total joint arthroplastyOpen Targets

0.25Weak

systemic lupus erythematosusOpen Targets

0.17Weak

alcohol drinkingOpen Targets

0.06Suggestive

hearing lossOpen Targets

0.04Suggestive

Abnormality of the skeletal systemOpen Targets

0.04Suggestive

neurotic disorderOpen Targets

0.03Suggestive

ovarian neoplasmOpen Targets

0.03Suggestive

facial painOpen Targets

0.03Suggestive

mathematical abilityOpen Targets

0.03Suggestive

hyperaldosteronismOpen Targets

0.03Suggestive

Abnormality of refractionOpen Targets

0.03Suggestive

smoking initiationOpen Targets

0.02Suggestive

AnxietyOpen Targets

0.02Suggestive

Pathogenic Variants

No pathogenic variants reported on ClinVar for this gene.

Tissue Expression6 tissues

Brain

100%

Lung

45%

Heart

33%

Bone Marrow

18%

Ovary

10%

Liver

Gene Interaction Network6 neighbors

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StructureAlphaFold

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AlphaFoldAI-predicted · UniProt A8MWY0

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ConstraintgnomAD v4.1

LOEUFⓘ

0.94LoF Tolerant

pLIⓘ

0.00Tolerant

Observed/Expected LoF0.76 [0.62–0.94]

Rankings2 dim

Where ELAPOR2 stands among ~20K protein-coding genes

#15,855of 20,598
Most Researched14
#8,734of 17,882
Most Constrained (LOEUF)0.94