GSKIP — GSK3B interacting protein

5 sources retrieved · Most recent: April 2026 · Index updated 5 months ago

36PubMed Papers

#10,812 · top 56% of 19K genes

20Diseases

top 60%

0Drugs

0Pathogenic Variants

Experimental GO EvidenceSwiss-Prot Reviewed

beta-catenin bindingprotein kinase inhibitor activityprotein bindingpositive regulation of canonical Wnt signaling pathwaySjogren syndromeCongenital pulmonary alveolar proteinosisneurodegenerative diseaseNeonatal acute respiratory distress with surfactant metabolism deficiency

AI Summary

AI summary not yet available. Showing NCBI Gene summary.

GSK3B interacting protein

⚠Limited data available — This gene has 0 indexed publications. Summary and analysis may be incomplete.

Disease Associations20

Sjogren syndromeOpen Targets

0.08Suggestive

Congenital pulmonary alveolar proteinosisOpen Targets

0.07Suggestive

neurodegenerative diseaseOpen Targets

0.07Suggestive

Neonatal acute respiratory distress with surfactant metabolism deficiencyOpen Targets

0.07Suggestive

isolated Pierre-Robin syndromeOpen Targets

0.06Suggestive

autoimmune pulmonary alveolar proteinosisOpen Targets

0.06Suggestive

Ankyloblepharon - ectodermal defects - cleft lip/palateOpen Targets

0.05Suggestive

Treacher-Collins syndromeOpen Targets

0.05Suggestive

cleft palateOpen Targets

0.05Suggestive

pachyonychia congenitaOpen Targets

0.05Suggestive

auriculocondylar syndromeOpen Targets

0.05Suggestive

van der Woude syndromeOpen Targets

0.05Suggestive

autosomal dominant hypohidrotic ectodermal dysplasiaOpen Targets

0.05Suggestive

Robinow syndromeOpen Targets

0.05Suggestive

meningiomaOpen Targets

0.05Suggestive

Ear-patella-short stature syndromeOpen Targets

0.05Suggestive

lethal osteosclerotic bone dysplasiaOpen Targets

0.05Suggestive

isolated congenital hypoglossia/aglossiaOpen Targets

0.05Suggestive

autosomal dominant Robinow syndromeOpen Targets

0.05Suggestive

Orofaciodigital syndrome type 2Open Targets

0.05Suggestive

Pathogenic Variants

No pathogenic variants reported on ClinVar for this gene.

Related Genes

No related genes found for this gene.

Tissue Expression

No tissue expression data available for this gene.

Gene Interaction Network

No interaction data available for this gene.

Structure1 PDB hit

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PDB1SGO · NMR

View on RCSB

ConstraintgnomAD v4.1

LOEUFⓘ

0.86LoF Tolerant

pLIⓘ

0.52Intermediate

Observed/Expected LoF0.33 [0.15–0.86]

Rankings2 dim

Where GSKIP stands among ~20K protein-coding genes

#10,785of 20,598
Most Researched36
#7,537of 17,882
Most Constrained (LOEUF)0.86