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0 sources retrieved · Most recent: April 2026 · Index updated 14 days ago
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IPO9
importin 9
Chromosome 1 · 1q32.1
NCBI Gene: 55705Ensembl: ENSG00000198700.11HGNC: HGNC:19425UniProt: Q96P70
139PubMed Papers
20Diseases
0Drugs
0Pathogenic Variants
FUNCTIONAL ROLE
Highly ConstrainedTransporter
DATA QUALITY
✓ Experimental GO Evidence✓ Swiss-Prot Reviewed
protein bindingproteasome localizationcytosolnucleoplasmAbnormality of the skeletal systeminsomnialate-onset Alzheimers diseaseplacental retention
✦AI Summary

AI summary not yet available. Showing NCBI Gene summary.

importin 9

⚠Limited data available — This gene has 0 indexed publications. Summary and analysis may be incomplete.
Disease Associationsⓘ20
Abnormality of the skeletal systemOpen Targets
0.38Weak
insomniaOpen Targets
0.28Weak
late-onset Alzheimers diseaseOpen Targets
0.27Weak
placental retentionOpen Targets
0.26Weak
type 2 diabetes mellitusOpen Targets
0.17Weak
hypertensionOpen Targets
0.15Weak
obesityOpen Targets
0.13Weak
essential hypertensionOpen Targets
0.12Weak
coronary artery diseaseOpen Targets
0.12Weak
major depressive disorderOpen Targets
0.10Weak
intelligenceOpen Targets
0.06Suggestive
abscessOpen Targets
0.06Suggestive
cellulitisOpen Targets
0.06Suggestive
diabetes mellitusOpen Targets
0.06Suggestive
autism spectrum disorderOpen Targets
0.06Suggestive
attention deficit hyperactivity disorderOpen Targets
0.05Suggestive
aortic stenosisOpen Targets
0.05Suggestive
coronary atherosclerosisOpen Targets
0.04Suggestive
venous thromboembolismOpen Targets
0.04Suggestive
nephrotic syndromeOpen Targets
0.04Suggestive
Pathogenic Variants
No pathogenic variants reported on ClinVar for this gene.
View on ClinVar ↗
Related Genes
IPO11Shared pathway100%H2BC11Protein interaction100%CFL1Protein interaction99%H2AC13Protein interaction97%H2AC4Protein interaction97%H2AC6Protein interaction97%
Tissue Expression6 tissues
Brain
100%
Heart
51%
Ovary
48%
Bone Marrow
47%
Lung
46%
Liver
40%
Gene Interaction Network
Click a node to explore
IPO9IPO11H2BC11CFL1H2AC13H2AC4H2AC6
PROTEIN STRUCTURE
Preparing viewer…
PDB6N1Z · 2.70 Å · X-ray
View on RCSB ↗
Constraintⓘ
LOEUFⓘ
0.31Highly Constrained
pLIⓘ
1.00Intolerant
Observed/Expected LoF0.22 [0.15–0.31]
RankingsWhere IPO9 stands among ~20K protein-coding genes
  • #3,310of 20,598
    Most Researched139 · top quartile
  • #1,221of 17,882
    Most Constrained (LOEUF)0.31 · top 10%
Genes detectedIPO9
Sources retrieved0 papers
Response time—