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10 sources retrieved · Most recent: April 2026 · Index updated 14 days ago
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LMLN
leishmanolysin like peptidase
Chromosome 3 · 3q29
NCBI Gene: 89782Ensembl: ENSG00000185621.12HGNC: HGNC:15991UniProt: B4DR62
19PubMed Papers
20Diseases
0Drugs
0Pathogenic Variants
FUNCTIONAL ROLE
Protease
DATA QUALITY
✓ Experimental GO Evidence✓ Swiss-Prot Reviewed
cytosolpeptidase activitycytoplasmlipid dropletalopecia areataprostate cancerFamilial prostate cancerneoplasm
✦AI Summary

Based on the provided abstracts, insufficient information is available to describe the function of LMLN (leishmanolysin like peptidase). While UniProt indicates it functions as a metalloprotease with peptidase activity in the cytosol and cytoplasm, the provided PubMed abstracts discuss unrelated topics including eye movement disorders (latent/manifest latent nystagmus), surgical procedures, lymph node measurements, Chinese patent medicines, and Schistosoma japonicum genomics. Only one abstract briefly mentions 'Lmln' in the context of Schistosoma japonicum evolution, suggesting it may relate to intermediate host specificity 1, but provides no mechanistic details about the gene's molecular function, disease relevance, or clinical significance. Additional literature specifically focused on LMLN gene function would be required to provide a comprehensive summary of its biological role and clinical importance.

Sources cited
1
Brief mention of Lmln in context of Schistosoma japonicum host specificity, but no functional details provided
PMID: 35385741
⚠Limited data available — This gene has 1 indexed publication. Summary and analysis may be incomplete.
Disease Associationsⓘ20
alopecia areataOpen Targets
0.24Weak
prostate cancerOpen Targets
0.12Weak
Familial prostate cancerOpen Targets
0.11Weak
neoplasmOpen Targets
0.11Weak
infectionOpen Targets
0.10Suggestive
nonpapillary renal cell carcinomaOpen Targets
0.07Suggestive
Miyoshi myopathyOpen Targets
0.07Suggestive
bacterial vaginosisOpen Targets
0.06Suggestive
male reproductive system diseaseOpen Targets
0.06Suggestive
preeclampsiaOpen Targets
0.05Suggestive
breast cancerOpen Targets
0.05Suggestive
cancerOpen Targets
0.04Suggestive
non-alcoholic steatohepatitisOpen Targets
0.04Suggestive
hepatocellular carcinomaOpen Targets
0.03Suggestive
mucositisOpen Targets
0.03Suggestive
stomatitisOpen Targets
0.03Suggestive
visceral LeishmaniasisOpen Targets
0.03Suggestive
inflammatory bowel diseaseOpen Targets
0.03Suggestive
Abruptio PlacentaeOpen Targets
0.03Suggestive
malariaOpen Targets
0.03Suggestive
Pathogenic Variants
No pathogenic variants reported on ClinVar for this gene.
View on ClinVar ↗
Related Genes
HABP2Shared pathway100%TINAGShared pathway100%C3Protein interaction88%CAPN15Shared pathway67%CIROPShared pathway67%ACANShared pathway50%
Tissue Expression6 tissues
Heart
100%
Ovary
87%
Bone Marrow
60%
Liver
48%
Brain
45%
Lung
38%
Gene Interaction Network
Click a node to explore
LMLNHABP2TINAGC3CAPN15CIROPACAN
PROTEIN STRUCTURE
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AlphaFoldAI-predicted · UniProt Q96KR4
View on AlphaFold ↗
RankingsWhere LMLN stands among ~20K protein-coding genes
  • #14,457of 20,598
    Most Researched19
Genes detectedLMLN
Sources retrieved10 papers
Response time—
📄 Sources
10▼
1
A normal ocular motor system model that simulates the dual-mode fast phases of latent/manifest latent nystagmus.
PMID: 11762236
Biol Cybern · 2001
1.00
2
Characteristics of foveating and defoveating fast phases in latent nystagmus.
PMID: 9699567
Invest Ophthalmol Vis Sci · 1998
0.90
3
Laparoscopic en bloc lower mediastinal lymph node dissection via transhiatal approach for adenocarcinoma of esophagogastric junction.
PMID: 33285434
Surg Oncol · 2021
0.80
4
Reference intervals of mesenteric lymph node size according to lymphocyte counts in asymptomatic children.
PMID: 32040486
PLoS One · 2020
0.70
5
Latent and congenital nystagmus in Down syndrome.
PMID: 10494944
J Neuroophthalmol · 1999
0.60