LRATD1 (LRAT domain containing 1) is a substrate protein of N-Myristoyltransferases (NMTs) identified through interactome analysis 1. The protein is predicted to play a role in cell morphology and motility based on functional annotations, though direct experimental evidence of its specific molecular function is limited. LRATD1 contains an LRAT domain and functions as a substrate for NMT1/2-mediated N-terminal myristoylation 1, a post-translational modification that typically regulates protein localization and function. The myristoylation of LRATD1 suggests involvement in cellular processes requiring membrane association or protein-protein interactions. While no disease-specific studies directly examine LRATD1, its identification as an NMT substrate places it within the broader context of PTM regulation affecting cell biology. The clinical significance of LRATD1 remains to be established, as functional studies characterizing its role in normal physiology and disease pathogenesis have not been reported in available literature. Further investigation is needed to elucidate LRATD1's specific cellular functions and potential involvement in disease processes.