Based on limited published evidence, LRRIQ1 is a leucine-rich repeat and IQ motif-containing protein associated with microtubule cytoskeleton organization. A genome-wide association study identified a locus at 12q21.31 containing LRRIQ1 associated with plasma inhibin B levels 1. The gene resides in a genomic region containing a distal enhancer (Alx1-DE1) that regulates ALX1 expression during craniofacial development, though this enhancer's presence within LRRIQ1 introns does not indicate direct LRRIQ1 function in this process 2.