Based on limited published evidence, MINDY4 is a probable cytosolic hydrolase with K48-linked deubiquitinase activity that catalyzes removal of lysine-48-linked polyubiquitin chains from protein substrates. UniProt and GO annotations establish its deubiquitination function, but specific protein targets and biological roles remain largely uncharacterized. The provided PubMed abstract concerns FAM188B, not MINDY4, and therefore does not provide direct evidence for MINDY4 function.