1 sources retrieved Β· Most recent: April 2026 Β· Index updated 15 days ago
βGeneE is for informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment.
25PubMed Papers
20Diseases
0Drugs
0Pathogenic Variants
DATA QUALITYβ Experimental GO Evidenceβ Swiss-Prot Reviewed
protein bindingidentical protein bindingtype 1 diabetes mellituspreeclampsiaovarian neoplasmataxia telangiectasia
Based on limited published evidence, MRFAP1L1 is a protein-binding protein belonging to the Morf4 family. Structurally, it exhibits identical protein binding and general protein binding capabilities according to Gene Ontology annotations. MRFAP1L1 was identified as a pyroptosis-related gene with significant expression differences between bladder cancer and normal tissue 1. It was selected as part of an 11-gene prognostic signature for predicting bladder cancer patient outcomes and survival, though its specific molecular mechanism remains undefined.
1
MRFAP1L1 identified as pyroptosis-related gene with differential expression in bladder cancer; included in prognostic risk model for predicting patient survival
PMID: 37849225β Limited data available β This gene has 1 indexed publication. Summary and analysis may be incomplete.
type 1 diabetes mellitusOpen Targets
ovarian neoplasmOpen Targets
ataxia telangiectasiaOpen Targets
ovarian carcinomaOpen Targets
ovarian cancerOpen Targets
chronic kidney diseaseOpen Targets
Alzheimer diseaseOpen Targets
hepatocellular carcinomaOpen Targets
breast cancerOpen Targets
ovarian serous adenocarcinomaOpen Targets
multiple myelomaOpen Targets
polycystic ovary syndromeOpen Targets
bladder transitional cell carcinomaOpen Targets
esophageal cancerOpen Targets
uterine corpus endometrial carcinomaOpen Targets
No pathogenic variants reported on ClinVar for this gene.