TRIM10 — tripartite motif containing 10 | GeneE

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5 sources retrieved · Most recent: April 2026 · Index updated 3 months ago

28PubMed Papers

#12,333 · top 63% of 19K genes

0Diseases

0Drugs

0Pathogenic Variants

Experimental GO EvidenceSwiss-Prot Reviewed

protein bindinginnate immune responseubiquitin protein ligase activitycytoplasm

AI Summary

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tripartite motif containing 10

⚠Limited data available — This gene has 0 indexed publications. Summary and analysis may be incomplete.

Pathogenic Variants

No pathogenic variants reported on ClinVar for this gene.

Related Genes6

TRIM59Shared pathway67%TMEFF1Shared pathway50%DEFB131BShared pathway50%DEFB131AShared pathway50%DEFB134Shared pathway50%TRIM74Shared pathway50%

Tissue Expression

No tissue expression data available for this gene.

Gene Interaction Network6 neighbors

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Structure1 PDB hit

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PDB7QS0 · 2.30 Å · X-ray

ConstraintgnomAD v4.1

LOEUFⓘ

1.29LoF Tolerant

pLIⓘ

0.00Tolerant

Observed/Expected LoF0.98 [0.76–1.29]

Rankings2 dim

Where TRIM10 stands among ~20K protein-coding genes

#12,471of 20,598
Most Researched28
#13,552of 17,882
Most Constrained (LOEUF)1.29

Meta

Genes detectedTRIM10

Sources retrieved5 papers

Response time—

Sources5

1

The tripartite motif family identifies cell compartments.

EMBO J · 2001

0.95

2

Molecular cloning of testis-abundant finger Protein/Ring finger protein 23 (RNF23), a novel RING-B box-coiled coil-B30.2 protein on the class I region of the human MHC.

Biochem Biophys Res Commun · 2000

0.95

3

HERF1, a novel hematopoiesis-specific RING finger protein, is required for terminal differentiation of erythroid cells.

Mol Cell Biol · 1999

0.95

4

Cloning, structural analysis, and mapping of the B30 and B7 multigenic families to the major histocompatibility complex (MHC) and other chromosomal regions.

Immunogenetics · 1997

0.95

5

Isolation of novel non-HLA gene fragments from the hemochromatosis region (6p21.3) by cDNA hybridization selection.

Am J Hum Genet · 1994

0.95

View all 28 papers on PubMed →