HomeAboutRankingsData Sources
Β© 2026 GeneE
🧬
GeneE
0 sources retrieved Β· Most recent: April 2026 Β· Index updated 14 days ago
β“˜GeneE is for informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment.
UQCC4
ubiquinol-cytochrome c reductase complex assembly factor 4
Chromosome 16 Β· 16p13.3
NCBI Gene: 283951Ensembl: ENSG00000174109.5HGNC: HGNC:27558UniProt: A0A0A8K8N9
8PubMed Papers
4Diseases
0Drugs
0Pathogenic Variants
FUNCTIONAL ROLE
Transporter
DATA QUALITY
βœ“ Experimental GO Evidenceβœ“ Swiss-Prot Reviewed
mitochondrionmitochondrial respiratory chain complex III assemblymitochondrial inner membraneprotein-membrane adaptor activityalcohol drinkingThromboembolisminvasive breast ductal carcinomaovarian serous cystadenocarcinoma
✦AI Summary

AI summary not yet available. Showing NCBI Gene summary.

ubiquinol-cytochrome c reductase complex assembly factor 4

⚠Limited data available β€” This gene has 0 indexed publications. Summary and analysis may be incomplete.
Disease Associationsβ“˜4
alcohol drinkingOpen Targets
0.03Suggestive
ThromboembolismOpen Targets
0.02Suggestive
invasive breast ductal carcinomaOpen Targets
0.00Suggestive
ovarian serous cystadenocarcinomaOpen Targets
0.00Suggestive
Pathogenic Variants
No pathogenic variants reported on ClinVar for this gene.
View on ClinVar β†—
Related Genes
UQCC1Shared pathway100%TTC19Shared pathway50%UQCC6Shared pathway50%UQCC5Shared pathway50%UQCC3Shared pathway33%LYRM7Shared pathway33%
Tissue Expression6 tissues
Liver
100%
Heart
90%
Brain
81%
Bone Marrow
74%
Ovary
69%
Lung
61%
Gene Interaction Network
Click a node to explore
UQCC4UQCC1TTC19UQCC6UQCC5UQCC3LYRM7
PROTEIN STRUCTURE
Preparing viewer…
AlphaFoldAI-predicted Β· UniProt Q4G0I0
View on AlphaFold β†—
Constraintβ“˜
LOEUFβ“˜
1.91LoF Tolerant
pLIβ“˜
0.01Tolerant
Observed/Expected LoF1.28 [0.58–1.91]
RankingsWhere UQCC4 stands among ~20K protein-coding genes
  • #17,745of 20,598
    Most Researched8
  • #17,317of 17,882
    Most Constrained (LOEUF)1.91
Genes detectedUQCC4
Sources retrieved0 papers
Response timeβ€”