UQCC4 — ubiquinol-cytochrome c reductase complex assembly factor 4

5 sources retrieved · Most recent: April 2026 · Index updated 6 months ago

8PubMed Papers

#17,660 · top 91% of 19K genes

5Diseases

top 97%

0Drugs

0Pathogenic Variants

TransporterExperimental GO EvidenceSwiss-Prot Reviewed

mitochondrionmitochondrial respiratory chain complex III assemblymitochondrial inner membraneprotein-membrane adaptor activityalcohol drinkingcolorectal carcinomainvasive ductal breast carcinomamucolipidosis

AI Summary

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ubiquinol-cytochrome c reductase complex assembly factor 4

⚠Limited data available — This gene has 0 indexed publications. Summary and analysis may be incomplete.

Disease Associations5

alcohol drinkingOpen Targets

0.04Suggestive

colorectal carcinomaOpen Targets

0.01Suggestive

invasive ductal breast carcinomaOpen Targets

0.00Suggestive

mucolipidosisOpen Targets

0.00Suggestive

ovarian serous cystadenocarcinomaOpen Targets

0.00Suggestive

Pathogenic Variants

No pathogenic variants reported on ClinVar for this gene.

Tissue Expression6 tissues

Liver

100%

Heart

90%

Brain

81%

Bone Marrow

74%

Ovary

69%

Lung

61%

Gene Interaction Network6 neighbors

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StructureAlphaFold

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AlphaFoldAI-predicted · UniProt Q4G0I0

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ConstraintgnomAD v4.1

LOEUFⓘ

1.91LoF Tolerant

pLIⓘ

0.01Tolerant

Observed/Expected LoF1.28 [0.58–1.91]

Rankings2 dim

Where UQCC4 stands among ~20K protein-coding genes

#17,745of 20,598
Most Researched8
#17,317of 17,882
Most Constrained (LOEUF)1.91