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GeneE
0 sources retrieved Β· Most recent: April 2026 Β· Index updated 14 days ago
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UQCC5
ubiquinol-cytochrome c reductase complex assembly factor 5
Chromosome 3 Β· 3p21.1
NCBI Gene: 440957Ensembl: ENSG00000168273.9HGNC: HGNC:37257UniProt: Q8WVI0
13PubMed Papers
20Diseases
0Drugs
0Pathogenic Variants
DATA QUALITY
βœ“ Experimental GO Evidenceβœ“ Swiss-Prot Reviewed
mitochondrial ribosome bindingmitochondrial respiratory chain complex IV assemblymitochondrial inner membranemitochondrionclear cell renal carcinomaintelligenceurinary bladder cancercataract
✦AI Summary

AI summary not yet available. Showing NCBI Gene summary.

ubiquinol-cytochrome c reductase complex assembly factor 5

⚠Limited data available β€” This gene has 0 indexed publications. Summary and analysis may be incomplete.
Disease Associationsβ“˜20
clear cell renal carcinomaOpen Targets
0.33Weak
intelligenceOpen Targets
0.22Weak
urinary bladder cancerOpen Targets
0.17Weak
cataractOpen Targets
0.13Weak
nonpapillary renal cell carcinomaOpen Targets
0.12Weak
attention deficit hyperactivity disorderOpen Targets
0.11Weak
Abnormality of the skeletal systemOpen Targets
0.11Weak
autism spectrum disorderOpen Targets
0.11Weak
schizophreniaOpen Targets
0.08Suggestive
bipolar disorderOpen Targets
0.08Suggestive
smoking behaviorOpen Targets
0.07Suggestive
ulcerative colitisOpen Targets
0.06Suggestive
neoplasmOpen Targets
0.04Suggestive
bipolar I disorderOpen Targets
0.04Suggestive
osteoarthritis, hipOpen Targets
0.03Suggestive
type 2 diabetes mellitusOpen Targets
0.03Suggestive
total hip arthroplastyOpen Targets
0.03Suggestive
mood disorderOpen Targets
0.03Suggestive
medical procedureOpen Targets
0.02Suggestive
diverticular diseaseOpen Targets
0.02Suggestive
Pathogenic Variants
No pathogenic variants reported on ClinVar for this gene.
View on ClinVar β†—
Related Genes
UQCC6Shared pathway100%UQCC1Shared pathway50%UQCC4Shared pathway50%PET117Shared pathway50%PET100Shared pathway50%COA5Shared pathway50%
Tissue Expression6 tissues
Heart
100%
Ovary
78%
Liver
51%
Lung
43%
Brain
19%
Bone Marrow
19%
Gene Interaction Network
Click a node to explore
UQCC5UQCC6UQCC1UQCC4PET117PET100COA5
PROTEIN STRUCTURE
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AlphaFoldAI-predicted Β· UniProt Q8WVI0
View on AlphaFold β†—
Constraintβ“˜
LOEUFβ“˜
1.57LoF Tolerant
pLIβ“˜
0.05Tolerant
Observed/Expected LoF0.72 [0.35–1.57]
RankingsWhere UQCC5 stands among ~20K protein-coding genes
  • #16,349of 20,598
    Most Researched13
  • #15,537of 17,882
    Most Constrained (LOEUF)1.57
Genes detectedUQCC5
Sources retrieved0 papers
Response timeβ€”