HomeAboutRankingsData Sources
Β© 2026 GeneE
🧬
GeneE
0 sources retrieved Β· Most recent: April 2026 Β· Index updated 14 days ago
β“˜GeneE is for informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment.
UQCC6
ubiquinol-cytochrome c reductase complex assembly factor 6
Chromosome 12 Β· 12q23.3
NCBI Gene: 728568Ensembl: ENSG00000204954.11HGNC: HGNC:34450UniProt: Q69YU5
14PubMed Papers
20Diseases
0Drugs
0Pathogenic Variants
DATA QUALITY
βœ“ Experimental GO Evidenceβœ“ Swiss-Prot Reviewed
protein bindingmitochondrial respiratory chain complex IV assemblymitochondrial respiratory chain complex III assemblymitochondrionneoplasmvenous thromboembolismcancerbreast cancer
✦AI Summary

AI summary not yet available. Showing NCBI Gene summary.

ubiquinol-cytochrome c reductase complex assembly factor 6

⚠Limited data available β€” This gene has 0 indexed publications. Summary and analysis may be incomplete.
Disease Associationsβ“˜20
neoplasmOpen Targets
0.08Suggestive
venous thromboembolismOpen Targets
0.03Suggestive
cancerOpen Targets
0.01Suggestive
breast cancerOpen Targets
0.01Suggestive
dilated cardiomyopathyOpen Targets
0.01Suggestive
AnxietyOpen Targets
0.01Suggestive
infectionOpen Targets
0.01Suggestive
colorectal carcinomaOpen Targets
0.01Suggestive
atrophic gastritisOpen Targets
0.01Suggestive
familial long QT syndromeOpen Targets
0.01Suggestive
hypertrophic cardiomyopathyOpen Targets
0.01Suggestive
small cell lung carcinomaOpen Targets
0.01Suggestive
strokeOpen Targets
0.01Suggestive
arrhythmogenic right ventricular cardiomyopathyOpen Targets
0.01Suggestive
breast carcinomaOpen Targets
0.01Suggestive
diffuse large B-cell lymphomaOpen Targets
0.01Suggestive
Miyoshi myopathyOpen Targets
0.01Suggestive
cervical cancerOpen Targets
0.01Suggestive
FeverOpen Targets
0.01Suggestive
neuroblastomaOpen Targets
0.01Suggestive
Pathogenic Variants
No pathogenic variants reported on ClinVar for this gene.
View on ClinVar β†—
Related Genes
UQCC5Shared pathway100%UQCC1Shared pathway50%UQCC4Shared pathway50%PET117Shared pathway50%PET100Shared pathway50%COA5Shared pathway50%
Tissue Expression6 tissues
Brain
100%
Ovary
76%
Heart
75%
Liver
57%
Lung
45%
Bone Marrow
36%
Gene Interaction Network
Click a node to explore
UQCC6UQCC5UQCC1UQCC4PET117PET100COA5
PROTEIN STRUCTURE
Preparing viewer…
AlphaFoldAI-predicted Β· UniProt Q69YU5
View on AlphaFold β†—
Constraintβ“˜
LOEUFβ“˜
1.88LoF Tolerant
pLIβ“˜
0.17Tolerant
Observed/Expected LoF0.88 [0.25–1.88]
RankingsWhere UQCC6 stands among ~20K protein-coding genes
  • #16,038of 20,598
    Most Researched14
  • #17,092of 17,882
    Most Constrained (LOEUF)1.88
Genes detectedUQCC6
Sources retrieved0 papers
Response timeβ€”