Based on limited published evidence, USP17L7 encodes a cysteine-type deubiquitinase localized to the cytosol and nucleus with annotated roles in regulating apoptotic processes and protein stability. However, no functional studies directly characterize its enzymatic activity or molecular mechanisms. USP17L7 copy number variations were associated with poor prognosis in lung squamous cell carcinoma patients 1 and showed association with gut microbiota composition 2, though the biological significance of these associations remains unclear.