WDCP (WD repeat and coiled coil containing protein) is a protein containing WD repeats and coiled-coil domains involved in kinase binding and protein complex oligomerization. Functionally, WDCP serves as a novel fusion partner for anaplastic lymphoma kinase (ALK), where its C-terminal proline-rich segment mediates binding to the Src homology 3 domain of Hck kinase, leading to tyrosine phosphorylation of WDCP 1. WDCP exists as an oligomer in mammalian cells, and when fused to ALK, the protein imposes an oligomeric structure that results in constitutive kinase activation and signaling 1. Clinically, elevated WDCP expression is associated with unfavorable prognosis in diffuse large B-cell lymphoma (DLBCL), identified as a prognostic biomarker in multi-gene risk stratification models 2. Additionally, WDCP was identified as a hub gene in lung adenocarcinoma pathways related to tumor progression 3. These findings suggest WDCP participates in oncogenic signaling pathways and may serve as a prognostic marker in hematologic and solid malignancies, though further functional characterization is warranted.