XNDC1N — XRCC1 N-terminal domain containing 1, N-terminal like

4 sources retrieved · Most recent: April 2026 · Index updated 7 months ago

4PubMed Papers

#18,774 · top 97% of 19K genes

8Diseases

top 95%

0Drugs

0Pathogenic Variants

Experimental GO EvidenceSwiss-Prot Reviewed

nucleolusdamaged DNA bindingsingle strand break repairnucleusAlzheimer diseaseMicroscopic hematuriaovarian serous cystadenocarcinomacervical cancer

AI Summary

AI summary not yet available. Showing NCBI Gene summary.

XRCC1 N-terminal domain containing 1, N-terminal like

⚠Limited data available — This gene has 0 indexed publications. Summary and analysis may be incomplete.

Disease Associations8

Alzheimer diseaseOpen Targets

0.06Suggestive

Microscopic hematuriaOpen Targets

0.02Suggestive

cervical cancerOpen Targets

0.00Suggestive

esophageal cancerOpen Targets

0.00Suggestive

hereditary breast carcinomaOpen Targets

0.00Suggestive

ovarian serous cystadenocarcinomaOpen Targets

0.00Suggestive

sarcomaOpen Targets

0.00Suggestive

uterine corpus endometrial carcinomaOpen Targets

0.00Suggestive

Pathogenic Variants

No pathogenic variants reported on ClinVar for this gene.

Tissue Expression6 tissues

Bone Marrow

100%

Ovary

85%

Liver

39%

Brain

35%

Heart

35%

Lung

33%

Gene Interaction Network6 neighbors

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StructureAlphaFold

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AlphaFoldAI-predicted · UniProt Q6ZNB5

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ConstraintgnomAD v4.1

LOEUFⓘ

1.86LoF Tolerant

pLIⓘ

0.32Tolerant

Observed/Expected LoF0.00 [0.00–1.86]

Rankings2 dim

Where XNDC1N stands among ~20K protein-coding genes

#18,793of 20,598
Most Researched4
#16,968of 17,882
Most Constrained (LOEUF)1.86