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GeneE
0 sources retrieved Β· Most recent: April 2026 Β· Index updated 15 days ago
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ZSCAN22
zinc finger and SCAN domain containing 22
Chromosome 19 Β· 19q13.43
NCBI Gene: 342945Ensembl: ENSG00000182318.8HGNC: HGNC:4929UniProt: P10073
21PubMed Papers
10Diseases
0Drugs
0Pathogenic Variants
FUNCTIONAL ROLE
Transcription Factor
DATA QUALITY
βœ“ Experimental GO Evidenceβœ“ Swiss-Prot Reviewed
protein bindingnucleusDNA-binding transcription factor activity, RNA polymerase II-specificRNA polymerase II cis-regulatory region sequence-specific DNA bindingmetabolic syndromebreast cancerasthmaesophageal squamous cell carcinoma
✦AI Summary

AI summary not yet available. Showing NCBI Gene summary.

zinc finger and SCAN domain containing 22

⚠Limited data available β€” This gene has 0 indexed publications. Summary and analysis may be incomplete.
Disease Associationsβ“˜10
metabolic syndromeOpen Targets
0.07Suggestive
breast cancerOpen Targets
0.01Suggestive
asthmaOpen Targets
0.01Suggestive
esophageal squamous cell carcinomaOpen Targets
0.01Suggestive
neoplasmOpen Targets
0.00Suggestive
metastatic melanomaOpen Targets
0.00Suggestive
gastric cancerOpen Targets
0.00Suggestive
glioma susceptibility 1Open Targets
0.00Suggestive
melanomaOpen Targets
0.00Suggestive
ovarian serous cystadenocarcinomaOpen Targets
0.00Suggestive
Pathogenic Variants
No pathogenic variants reported on ClinVar for this gene.
View on ClinVar β†—
Related Genes
ZSCAN32Protein interaction85%SCAND1Protein interaction82%ZSCAN20Protein interaction80%
Tissue Expression6 tissues
Liver
100%
Ovary
71%
Lung
57%
Heart
41%
Brain
37%
Bone Marrow
30%
Gene Interaction Network
Click a node to explore
ZSCAN22ZSCAN32SCAND1ZSCAN20
PROTEIN STRUCTURE
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AlphaFoldAI-predicted Β· UniProt P10073
View on AlphaFold β†—
Constraintβ“˜
LOEUFβ“˜
0.98LoF Tolerant
pLIβ“˜
0.06Tolerant
Observed/Expected LoF0.52 [0.30–0.98]
RankingsWhere ZSCAN22 stands among ~20K protein-coding genes
  • #14,089of 20,598
    Most Researched21
  • #9,436of 17,882
    Most Constrained (LOEUF)0.98
Genes detectedZSCAN22
Sources retrieved0 papers
Response timeβ€”