2 sources retrieved · Most recent: April 2026 · Index updated 14 days ago
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17PubMed Papers
20Diseases
0Drugs
0Pathogenic Variants
DATA QUALITY✓ Swiss-Prot Reviewed
nucleusAbnormality of the skeletal systemasthmabenign neoplasmchronic rhinosinusitis with nasal polyps
Based on limited published evidence, BRD10 is a bromodomain-containing protein located on chromosome 9. The primary functional information derives from its identification as one of 24 genes prioritized in comprehensive genomic analyses of 9p deletion syndrome 12. BRD10 was selected based on statistical assessment of human genomic variation and spatial transcriptomics of embryonic mouse tissue, indicating relevance to craniofacial and brain development. The gene is implicated in the phenotypic manifestations affecting the majority (83%) of individuals with 9p deletion syndrome, though specific molecular functions remain to be elucidated.
1
BRD10 identified as one of 24 important genes for majority of 9p deletion syndrome cases through WGS analysis and spatial transcriptomics
PMID: 401962532
BRD10 prioritized as important gene for 9p deletion syndrome through statistical genomic assessment and spatial transcriptomics of embryonic mouse tissue
PMID: 41137173⚠Limited data available — This gene has 2 indexed publications. Summary and analysis may be incomplete.
Abnormality of the skeletal systemOpen Targets
benign neoplasmOpen Targets
chronic rhinosinusitis with nasal polypsOpen Targets
multiple sclerosisOpen Targets
adult onset asthmaOpen Targets
childhood onset asthmaOpen Targets
allergic rhinitisOpen Targets
B-cell acute lymphoblastic leukemiaOpen Targets
chronic rhinosinusitisOpen Targets
respiratory system diseaseOpen Targets
allergic diseaseOpen Targets
deep vein thrombosisOpen Targets
respiratory tract infectious disorderOpen Targets
protozoa infectious diseaseOpen Targets
lower respiratory tract diseaseOpen Targets
Abnormal thrombosisOpen Targets
No pathogenic variants reported on ClinVar for this gene.