2 sources retrieved · Most recent: April 2026 · Index updated 15 days ago
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21PubMed Papers
20Diseases
0Drugs
0Pathogenic Variants
DATA QUALITY✓ Experimental GO Evidence✓ Swiss-Prot Reviewed
protein bindingprotein localization to perinuclear region of cytoplasmprotein transport along microtubulegastroesophageal reflux diseaseAbruptio Placentaemathematical abilityintelligence
Based on limited published evidence, FHIP1A is a probable component of the FTS/Hook/FHIP (FHF) complex that promotes AP-4 complex distribution to the perinuclear region 1. The protein participates in protein binding and transport along microtubules to facilitate perinuclear protein localization. A genomic region near FHIP1A shows association with LDL cholesterol levels in African populations 2. Additionally, the divergent transcript FHIP1A-DT functions as a long non-coding RNA with potential diagnostic and prognostic significance in colorectal cancer 3.
1
FHIP1A is a component of the FHF complex that promotes AP-4 distribution to perinuclear region
PMID: 320739972
FHIP1A genomic region associates with LDL cholesterol levels in sub-Saharan African populations
PMID: 355461423
FHIP1A-DT lncRNA has diagnostic and prognostic potential in colorectal cancer
PMID: 37703762⚠Limited data available — This gene has 3 indexed publications. Summary and analysis may be incomplete.
gastroesophageal reflux diseaseOpen Targets
Abruptio PlacentaeOpen Targets
mathematical abilityOpen Targets
Alzheimer diseaseOpen Targets
pathological myopiaOpen Targets
Blackfan-Diamond anemiaOpen Targets
hereditary persistence of fetal hemoglobin-sickle cell disease syndromeOpen Targets
Hereditary persistence of fetal hemoglobin - beta-thalassemiaOpen Targets
inosine triphosphatase deficiencyOpen Targets
alpha thalassemia-intellectual disability syndrome type 1Open Targets
Alpha-thalassemia - intellectual disability syndrome linked to chromosome 16Open Targets
Alpha-thalassemia - myelodysplastic syndromeOpen Targets
alpha-thalassemia-myelodysplastic syndromeOpen Targets
primary familial polycythemia due to EPO receptor mutationOpen Targets
Autosomal dominant methemoglobinemiaOpen Targets
No pathogenic variants reported on ClinVar for this gene.