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GeneE
0 sources retrieved Β· Most recent: April 2026 Β· Index updated 14 days ago
β“˜GeneE is for informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment.
H2BC13
H2B clustered histone 13
Chromosome 6 Β· 6p22.1
NCBI Gene: 8340Ensembl: ENSG00000185130.6HGNC: HGNC:4748UniProt: Q99880
101PubMed Papers
20Diseases
0Drugs
0Pathogenic Variants
FUNCTIONAL ROLE
Hub Gene
DATA QUALITY
βœ“ Experimental GO Evidenceβœ“ Swiss-Prot Reviewed
protein bindingextracellular exosomenucleuschromatin organizationviral diseaseinfectious diseasebreast carcinomamelanoma
✦AI Summary

AI summary not yet available. Showing NCBI Gene summary.

H2B clustered histone 13

⚠Limited data available β€” This gene has 0 indexed publications. Summary and analysis may be incomplete.
Disease Associationsβ“˜20
infectious diseaseOpen Targets
0.50Moderate
viral diseaseOpen Targets
0.50Moderate
breast carcinomaOpen Targets
0.39Weak
melanomaOpen Targets
0.37Weak
cancerOpen Targets
0.37Weak
dengue diseaseOpen Targets
0.37Weak
actinic keratosisOpen Targets
0.05Suggestive
sebaceous of Jadassohn nevusOpen Targets
0.04Suggestive
laryngotracheoesophageal cleftOpen Targets
0.01Suggestive
lung adenocarcinomaOpen Targets
0.01Suggestive
systemic lupus erythematosusOpen Targets
0.01Suggestive
neoplasmOpen Targets
0.01Suggestive
pneumoniaOpen Targets
0.01Suggestive
autoimmune diseaseOpen Targets
0.00Suggestive
osteoarthritisOpen Targets
0.00Suggestive
hepatocellular carcinomaOpen Targets
0.00Suggestive
endometrial cancerOpen Targets
0.00Suggestive
lung cancerOpen Targets
0.00Suggestive
acute myeloid leukemiaOpen Targets
0.00Suggestive
bipolar disorderOpen Targets
0.00Suggestive
Pathogenic Variants
No pathogenic variants reported on ClinVar for this gene.
View on ClinVar β†—
Related Genes
H2BC3Shared pathway100%H2BC9Shared pathway100%H2BC15Shared pathway100%CDC73Protein interaction100%CTR9Protein interaction100%RTF1Protein interaction100%
Tissue Expression6 tissues
Bone Marrow
100%
Brain
3%
Ovary
2%
Lung
1%
Liver
0%
Heart
0%
Gene Interaction Network
Click a node to explore
H2BC13H2BC3H2BC9H2BC15CDC73CTR9RTF1
PROTEIN STRUCTURE
Preparing viewer…
AlphaFoldAI-predicted Β· UniProt Q99880
View on AlphaFold β†—
Constraintβ“˜
LOEUFβ“˜
1.96LoF Tolerant
pLIβ“˜
0.00Tolerant
Observed/Expected LoF1.85 [1.08–1.96]
RankingsWhere H2BC13 stands among ~20K protein-coding genes
  • #4,718of 20,598
    Most Researched101 Β· top quartile
  • #17,750of 17,882
    Most Constrained (LOEUF)1.96
Genes detectedH2BC13
Sources retrieved0 papers
Response timeβ€”