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GeneE
0 sources retrieved Β· Most recent: April 2026 Β· Index updated 14 days ago
β“˜GeneE is for informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment.
H2BW2
H2B.W histone 2
Chromosome X Β· Xq22.2
NCBI Gene: 286436Ensembl: ENSG00000101812.15HGNC: HGNC:27867UniProt: P0C1H6
8PubMed Papers
20Diseases
0Drugs
0Pathogenic Variants
DATA QUALITY
βœ“ Experimental GO Evidenceβœ“ Swiss-Prot Reviewed
DNA bindingstructural constituent of chromatinchromatin organizationnucleusinfectionneoplasmbreast cancercancer
✦AI Summary

AI summary not yet available. Showing NCBI Gene summary.

H2B.W histone 2

⚠Limited data available β€” This gene has 0 indexed publications. Summary and analysis may be incomplete.
Disease Associationsβ“˜20
infectionOpen Targets
0.02Suggestive
neoplasmOpen Targets
0.02Suggestive
breast cancerOpen Targets
0.02Suggestive
cancerOpen Targets
0.02Suggestive
systemic lupus erythematosusOpen Targets
0.02Suggestive
goutOpen Targets
0.01Suggestive
prostate cancerOpen Targets
0.01Suggestive
posterior cortical atrophyOpen Targets
0.01Suggestive
gliomaOpen Targets
0.01Suggestive
lung cancerOpen Targets
0.01Suggestive
meningitisOpen Targets
0.01Suggestive
glioblastomaOpen Targets
0.01Suggestive
non-small cell lung carcinomaOpen Targets
0.01Suggestive
ovarian cancerOpen Targets
0.01Suggestive
neuroblastomaOpen Targets
0.01Suggestive
visceral LeishmaniasisOpen Targets
0.01Suggestive
ovarian serous adenocarcinomaOpen Targets
0.01Suggestive
hepatocellular carcinomaOpen Targets
0.01Suggestive
colorectal carcinomaOpen Targets
0.00Suggestive
glioblastoma multiformeOpen Targets
0.00Suggestive
Pathogenic Variants
No pathogenic variants reported on ClinVar for this gene.
View on ClinVar β†—
Related Genes
HIRIP3Shared pathway100%HMGN3Shared pathway100%HMGN4Shared pathway100%MSL3Shared pathway100%KLF12Shared pathway100%FAM50BShared pathway100%
Tissue Expression6 tissues
Ovary
100%
Brain
56%
Lung
7%
Liver
3%
Bone Marrow
3%
Heart
0%
Gene Interaction Network
Click a node to explore
H2BW2HIRIP3HMGN3HMGN4MSL3KLF12FAM50B
PROTEIN STRUCTURE
Preparing viewer…
PDB9JC6 Β· 3.34 Γ… Β· EM
View on RCSB β†—
Constraintβ“˜
LOEUFβ“˜
1.57LoF Tolerant
pLIβ“˜
0.00Tolerant
Observed/Expected LoF0.87 [0.51–1.57]
RankingsWhere H2BW2 stands among ~20K protein-coding genes
  • #17,613of 20,598
    Most Researched8
  • #15,515of 17,882
    Most Constrained (LOEUF)1.57
Genes detectedH2BW2
Sources retrieved0 papers
Response timeβ€”