Based on limited published evidence, LCA5L (lebercilin LCA5 like) is a protein involved in ciliary biology with annotations indicating roles in protein binding, axoneme structure, and intraciliary transport. A genome-wide association study identified LCA5L as part of a risk locus (rs2837022) associated with non-suicidal self-injury, with colocalization evidence suggesting nearby SH3BGR/GET1 expression in the hippocampus contributes to this phenotype 1. LCA5L was also identified as a down-regulated protein in liver tissues of non-alcoholic steatohepatitis patients 2. However, direct functional characterization of LCA5L remains limited.