1 sources retrieved · Most recent: April 2026 · Index updated 14 days ago
ⓘGeneE is for informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment.
7PubMed Papers
1Diseases
0Drugs
0Pathogenic Variants
DATA QUALITY✓ Experimental GO Evidence✓ Swiss-Prot Reviewed
detection of chemical stimulus involved in sensory perception of smellolfactory receptor activityplasma membraneG protein-coupled receptor activityheart failure
OR2A2 is an olfactory receptor functioning as a G-protein coupled receptor involved in odorant detection and sensory perception of smell. Based on limited published evidence, OR2A2 has been identified as a gene with CpG sites near its locus that show altered DNA methylation patterns in response to prenatal phthalate exposure, particularly in female infants 1. The functional significance of these methylation changes and their impact on OR2A2 olfactory receptor activity remain unclear.
1
DNA methylation at CpG sites near OR2A2 is associated with neonatal phthalate (MnBP) exposure in female infants
PMID: 37120575⚠Limited data available — This gene has 1 indexed publication. Summary and analysis may be incomplete.
heart failureOpen Targets
No pathogenic variants reported on ClinVar for this gene.