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GeneE
1 sources retrieved · Most recent: April 2026 · Index updated 14 days ago
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OR9G9
olfactory receptor family 9 subfamily G member 9
Chromosome 11 · 11q11
NCBI Gene: 504191Ensembl: ENSG00000262191.1HGNC: HGNC:31940UniProt: A0A126GVB8
2PubMed Papers
0Diseases
0Drugs
0Pathogenic Variants
DATA QUALITY
✓ Swiss-Prot Reviewed
G protein-coupled receptor activityolfactory receptor activityG protein-coupled receptor signaling pathwaydetection of chemical stimulus involved in sensory perception of smell
✦AI Summary

Based on limited published evidence, OR9G9 is an olfactory receptor family protein located on chromosome 11. While its primary molecular function relates to olfactory signal transduction, a whole exome sequencing study identified OR9G9 as carrying significantly increased pathogenic variation in patients with complicated pneumococcal pneumonia (empyema) compared to controls 1. The study notes that OR9G9 associations have been previously related to viral infectious diseases, suggesting a potential role in host immune susceptibility to respiratory infections, though mechanistic details remain unclear.

Sources cited
1
Identified OR9G9 as carrying significantly increased pathogenic variation in pneumococcal empyema patients; noted prior associations with viral infectious diseases
PMID: 29751582
⚠Limited data available — This gene has 1 indexed publication. Summary and analysis may be incomplete.
Pathogenic Variants
No pathogenic variants reported on ClinVar for this gene.
View on ClinVar ↗
Related Genes
OR1F1Shared pathway100%OR2C1Shared pathway100%OR3A1Shared pathway100%OR1A1Shared pathway100%OR3A3Shared pathway100%OR1R1Shared pathway100%
Tissue Expression

No tissue expression data available for this gene.

Gene Interaction Network
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OR9G9OR1F1OR2C1OR3A1OR1A1OR3A3OR1R1
PROTEIN STRUCTURE
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AlphaFoldAI-predicted · UniProt A0A126GVB8
View on AlphaFold ↗
RankingsWhere OR9G9 stands among ~20K protein-coding genes
  • #19,204of 20,598
    Most Researched2
Genes detectedOR9G9
Sources retrieved1 papers
Response time—
📄 Sources
1
1
Whole Exome Sequencing Identifies New Host Genomic Susceptibility Factors in Empyema Caused by Streptococcus pneumoniae in Children: A Pilot Study.
PMID: 29751582
Genes (Basel) · 2018
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