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GeneE
0 sources retrieved Β· Most recent: April 2026 Β· Index updated 14 days ago
β“˜GeneE is for informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment.
TLE7
TLE family member 7
Chromosome 16 Β· 16q22.2
NCBI Gene: 102723796Ensembl: ENSG00000260734.7HGNC: HGNC:53648UniProt: A0A1W2PR48
1PubMed Papers
20Diseases
0Drugs
0Pathogenic Variants
DATA QUALITY
βœ“ Experimental GO Evidenceβœ“ Swiss-Prot Reviewed
transcription corepressor activitynegative regulation of canonical Wnt signaling pathwaynucleustranscription regulator complexinfectionmyopathycoronary artery diseaseDown syndrome
✦AI Summary

AI summary not yet available. Showing NCBI Gene summary.

TLE family member 7

⚠Limited data available β€” This gene has 0 indexed publications. Summary and analysis may be incomplete.
Disease Associationsβ“˜20
infectionOpen Targets
0.06Suggestive
myopathyOpen Targets
0.05Suggestive
coronary artery diseaseOpen Targets
0.04Suggestive
Down syndromeOpen Targets
0.04Suggestive
smoking initiationOpen Targets
0.04Suggestive
HydrocephalusOpen Targets
0.03Suggestive
HypercholesterolemiaOpen Targets
0.03Suggestive
risk-taking behaviourOpen Targets
0.03Suggestive
atherosclerosisOpen Targets
0.03Suggestive
ovarian neoplasmOpen Targets
0.02Suggestive
bacterial diseaseOpen Targets
0.02Suggestive
breast carcinomaOpen Targets
0.02Suggestive
glomerulonephritisOpen Targets
0.02Suggestive
Insulin resistanceOpen Targets
0.01Suggestive
Zika virus infectious diseaseOpen Targets
0.01Suggestive
Alzheimer diseaseOpen Targets
0.01Suggestive
tauopathyOpen Targets
0.01Suggestive
Mobius syndromeOpen Targets
0.00Suggestive
colonic neoplasmOpen Targets
0.00Suggestive
fetal growth restrictionOpen Targets
0.00Suggestive
Pathogenic Variants
No pathogenic variants reported on ClinVar for this gene.
View on ClinVar β†—
Related Genes
TLE4Shared pathway100%TMEM131LShared pathway100%CSNK1A1LShared pathway100%TMEM278Shared pathway100%TMEM170BShared pathway100%TPBGLShared pathway100%
Tissue Expression6 tissues
Lung
0%
Bone Marrow
0%
Heart
0%
Ovary
0%
Liver
0%
Brain
0%
Gene Interaction Network
Click a node to explore
TLE7TLE4TMEM131LCSNK1A1LTMEM278TMEM170BTPBGL
PROTEIN STRUCTURE
Preparing viewer…
AlphaFoldAI-predicted Β· UniProt A0A1W2PR48
View on AlphaFold β†—
RankingsWhere TLE7 stands among ~20K protein-coding genes
  • #19,443of 20,598
    Most Researched1
Genes detectedTLE7
Sources retrieved0 papers
Response timeβ€”