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0 sources retrieved Β· Most recent: April 2026 Β· Index updated 15 days ago
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CLPSL1
colipase like 1
Chromosome 6 Β· 6p21.31
NCBI Gene: 340204Ensembl: ENSG00000204140.10HGNC: HGNC:21251UniProt: A2RUU4
7PubMed Papers
16Diseases
0Drugs
0Pathogenic Variants
DATA QUALITY
βœ“ Experimental GO Evidenceβœ“ Swiss-Prot Reviewed
enzyme activator activitydigestionlipid catabolic processextracellular regionresponse to statinHashimoto's thyroiditispsoriasis vulgarisHematemesis
✦AI Summary

AI summary not yet available. Showing NCBI Gene summary.

colipase like 1

⚠Limited data available β€” This gene has 0 indexed publications. Summary and analysis may be incomplete.
Disease Associationsβ“˜16
response to statinOpen Targets
0.16Weak
Hashimoto's thyroiditisOpen Targets
0.14Weak
psoriasis vulgarisOpen Targets
0.14Weak
HematemesisOpen Targets
0.06Suggestive
celiac diseaseOpen Targets
0.04Suggestive
ulcerative colitisOpen Targets
0.03Suggestive
thyroid diseaseOpen Targets
0.03Suggestive
non-small cell lung carcinomaOpen Targets
0.01Suggestive
triple-negative breast cancerOpen Targets
0.01Suggestive
breast cancerOpen Targets
0.00Suggestive
colorectal carcinomaOpen Targets
0.00Suggestive
neoplasmOpen Targets
0.00Suggestive
Laurence-Moon syndromeOpen Targets
0.00Suggestive
Hereditary breast cancerOpen Targets
0.00Suggestive
hereditary breast carcinomaOpen Targets
0.00Suggestive
ovarian serous cystadenocarcinomaOpen Targets
0.00Suggestive
Pathogenic Variants
No pathogenic variants reported on ClinVar for this gene.
View on ClinVar β†—
Related Genes
LRCOL1Shared pathway100%CLPSL2Shared pathway100%CLPSShared pathway50%GKN1Shared pathway33%CAPN9Shared pathway33%PGCShared pathway33%
Tissue Expression6 tissues
Brain
100%
Bone Marrow
29%
Ovary
0%
Lung
0%
Liver
0%
Heart
0%
Gene Interaction Network
Click a node to explore
CLPSL1LRCOL1CLPSL2CLPSGKN1CAPN9PGC
PROTEIN STRUCTURE
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AlphaFoldAI-predicted Β· UniProt A2RUU4
View on AlphaFold β†—
Constraintβ“˜
LOEUFβ“˜
1.87LoF Tolerant
pLIβ“˜
0.00Tolerant
Observed/Expected LoF1.24 [0.73–1.87]
RankingsWhere CLPSL1 stands among ~20K protein-coding genes
  • #17,806of 20,598
    Most Researched7
  • #16,988of 17,882
    Most Constrained (LOEUF)1.87
Genes detectedCLPSL1
Sources retrieved0 papers
Response timeβ€”