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GeneE
0 sources retrieved Β· Most recent: April 2026 Β· Index updated 15 days ago
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LRCOL1
leucine rich colipase like 1
Chromosome 12 Β· 12q24.33
NCBI Gene: 100507055Ensembl: ENSG00000204583.11HGNC: HGNC:44160UniProt: A6NCL2
4PubMed Papers
7Diseases
0Drugs
0Pathogenic Variants
DATA QUALITY
βœ“ Swiss-Prot Reviewed
enzyme activator activitydigestionlipid catabolic processextracellular regionneurodegenerative diseaseatrial fibrillationbrain aneurysmhepatocellular carcinoma
✦AI Summary

AI summary not yet available. Showing NCBI Gene summary.

leucine rich colipase like 1

⚠Limited data available β€” This gene has 0 indexed publications. Summary and analysis may be incomplete.
Disease Associationsβ“˜7
neurodegenerative diseaseOpen Targets
0.27Weak
atrial fibrillationOpen Targets
0.18Weak
brain aneurysmOpen Targets
0.15Weak
hepatocellular carcinomaOpen Targets
0.05Suggestive
COVID-19Open Targets
0.02Suggestive
ovarian dysfunctionOpen Targets
0.02Suggestive
cervical cancerOpen Targets
0.00Suggestive
Pathogenic Variants
No pathogenic variants reported on ClinVar for this gene.
View on ClinVar β†—
Related Genes
CLPSL1Shared pathway100%CLPSL2Shared pathway100%FAM229BProtein interaction70%CLPSShared pathway50%GKN1Shared pathway33%CAPN9Shared pathway33%
Tissue Expression6 tissues
Liver
100%
Lung
11%
Bone Marrow
3%
Ovary
2%
Heart
1%
Brain
0%
Gene Interaction Network
Click a node to explore
LRCOL1CLPSL1CLPSL2FAM229BCLPSGKN1CAPN9
PROTEIN STRUCTURE
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AlphaFoldAI-predicted Β· UniProt A6NCL2
View on AlphaFold β†—
Constraintβ“˜
LOEUFβ“˜
1.47LoF Tolerant
pLIβ“˜
0.00Tolerant
Observed/Expected LoF1.01 [0.71–1.47]
RankingsWhere LRCOL1 stands among ~20K protein-coding genes
  • #18,607of 20,598
    Most Researched4
  • #14,978of 17,882
    Most Constrained (LOEUF)1.47
Genes detectedLRCOL1
Sources retrieved0 papers
Response timeβ€”