1 sources retrieved Β· Most recent: April 2026 Β· Index updated 15 days ago
βGeneE is for informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment.
19PubMed Papers
20Diseases
0Drugs
0Pathogenic Variants
FUNCTIONAL ROLETransporter
DATA QUALITYβ Experimental GO Evidenceβ Swiss-Prot Reviewed
protein bindingstructural constituent of nuclear porenucleocytoplasmic transportnuclear envelopealcoholic pancreatitisosteoarthritis, kneeosteoarthritis, hipmedical procedure
NUP62CL is a nucleoporin 62 C-terminal-like protein with protein binding capability. Based on limited published evidence, NUP62CL expression correlates with clinical outcomes in lung adenocarcinoma, with low expression associated with improved prognosis 1. High NUP62CL expression significantly predicts worse survival outcomes and correlates with advanced clinical staging 1. Gene set enrichment analysis suggests involvement in telomere recombination and maintenance pathways 1. NUP62CL expression positively correlates with infiltration of B lymphocytes and memory CD4+ T cells in lung adenocarcinoma 1.
1
Low NUP62CL expression indicates good prognosis in lung adenocarcinoma; high expression predicts worse survival and correlates with advanced clinical stage; involvement in telomere maintenance pathways; positive correlation with tumor-infiltrating B lymphocytes and memory CD4+ T cells
PMID: 33934535β Limited data available β This gene has 1 indexed publication. Summary and analysis may be incomplete.
alcoholic pancreatitisOpen Targets
osteoarthritis, kneeOpen Targets
osteoarthritis, hipOpen Targets
medical procedureOpen Targets
oral squamous cell carcinomaOpen Targets
isolated asymptomatic elevation of creatine phosphokinaseOpen Targets
lung adenocarcinomaOpen Targets
hemolytic anemia due to glutathione reductase deficiencyOpen Targets
Fuchs endothelial corneal dystrophyOpen Targets
granular corneal dystrophy type IOpen Targets
pseudohyperaldosteronism type 2Open Targets
X-linked endothelial corneal dystrophyOpen Targets
lattice corneal dystrophy type IOpen Targets
granular corneal dystrophy type IIOpen Targets
Familial ocular anterior segment mesenchymal dysgenesisOpen Targets
hemolytic anemia due to erythrocyte adenosine deaminase overproductionOpen Targets
cataract - microcornea syndromeOpen Targets
Cataract-microcornea syndromeOpen Targets
No pathogenic variants reported on ClinVar for this gene.