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0 sources retrieved · Most recent: April 2026 · Index updated 14 days ago
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SDAD1
SDA1 domain containing 1
Chromosome 4 · 4q21.1
NCBI Gene: 55153Ensembl: ENSG00000198301.12HGNC: HGNC:25537UniProt: B4DT66
94PubMed Papers
20Diseases
0Drugs
0Pathogenic Variants
FUNCTIONAL ROLE
Hub GeneTransporter
DATA QUALITY
✓ Experimental GO Evidence✓ Swiss-Prot Reviewed
nucleolusribosomal large subunit export from nucleusribosomal large subunit biogenesisplacenta praeviadevice complicationneurodegenerative diseaseinfection
✦AI Summary

AI summary not yet available. Showing NCBI Gene summary.

SDA1 domain containing 1

⚠Limited data available — This gene has 0 indexed publications. Summary and analysis may be incomplete.
Disease Associationsⓘ20
placenta praeviaOpen Targets
0.34Weak
device complicationOpen Targets
0.27Weak
neurodegenerative diseaseOpen Targets
0.16Weak
infectionOpen Targets
0.03Suggestive
familial hemolytic anemiaOpen Targets
0.02Suggestive
osteoporosisOpen Targets
0.01Suggestive
colorectal cancerOpen Targets
0.01Suggestive
juvenile dermatomyositisOpen Targets
0.01Suggestive
psoriasisOpen Targets
0.01Suggestive
AIDSOpen Targets
0.01Suggestive
allergic rhinitisOpen Targets
0.01Suggestive
cardiac hypertrophyOpen Targets
0.01Suggestive
gastric cancerOpen Targets
0.01Suggestive
acquired immunodeficiencyOpen Targets
0.01Suggestive
cancerOpen Targets
0.01Suggestive
chronic obstructive pulmonary diseaseOpen Targets
0.00Suggestive
neoplasmOpen Targets
0.00Suggestive
hypertrophyOpen Targets
0.00Suggestive
severe acute respiratory syndromeOpen Targets
0.00Suggestive
Nijmegen breakage syndromeOpen Targets
0.00Suggestive
Pathogenic Variants
No pathogenic variants reported on ClinVar for this gene.
View on ClinVar ↗
Related Genes
UTP3Protein interaction100%NAT10Protein interaction99%MPHOSPH10Protein interaction99%NOL8Protein interaction97%PDCD11Protein interaction95%PES1Protein interaction94%
Tissue Expression6 tissues
Heart
100%
Brain
66%
Ovary
44%
Lung
42%
Bone Marrow
42%
Liver
34%
Gene Interaction Network
Click a node to explore
SDAD1UTP3NAT10MPHOSPH10NOL8PDCD11PES1
PROTEIN STRUCTURE
Preparing viewer…
PDB8FL3 · 2.53 Å · EM
View on RCSB ↗
Constraintⓘ
LOEUFⓘ
0.93LoF Tolerant
pLIⓘ
0.00Tolerant
Observed/Expected LoF0.73 [0.57–0.93]
RankingsWhere SDAD1 stands among ~20K protein-coding genes
  • #5,105of 20,598
    Most Researched94 · top quartile
  • #8,614of 17,882
    Most Constrained (LOEUF)0.93
Genes detectedSDAD1
Sources retrieved0 papers
Response time—