Based on limited published evidence, STMND1 (stathmin domain containing 1) is a phylogenetically ancient stathmin protein that binds tubulin dimers and localizes to motile cilia 1. The protein features a N-terminal myristoylated and palmitoylated motif directing membrane localization and a tubulin-binding stathmin-like domain containing an internal nuclear localization signal 1. STMND1 exhibits tubulin-dependent nuclear translocation, with soluble tubulin concentration inhibiting this translocation 1. Highly expressed in multiciliated epithelial cells, STMND1 overexpression increases primary cilia length 1. GO annotations suggest involvement in microtubule depolymerization and regulation of microtubule polymerization, with roles in neuronal development.