Most Researched

Genes ranked by total PubMed publication count — the most-studied genes in biology.

Filter by chromosome
251300 of 20,598 genesranked by Most Researched
#GeneNameChrTagsPubMed Papers
251MMP3matrix metallopeptidase 311Hub GeneProtease
792
252CBLCbl proto-oncogene11Hub GeneOncogene
785
253ALBalbumin4Hub GeneOMIM Disease Gene
784
254LPLlipoprotein lipase8Hub GeneOMIM Disease Gene
784
255BCL2L1BCL2 like 120Highly ConstrainedHub Gene
780
256CXCL10C-X-C motif chemokine ligand 104Hub GeneClinical Trials
776
257GJA1gap junction protein alpha 16Hub GeneOMIM Disease Gene
773
258PCSK9proprotein convertase subtilisin/kexin type 91ProteaseFDA Approved Target
771
259TIMP1TIMP metallopeptidase inhibitor 1XHub GeneHighly Studied
770
260BSGbasigin (Ok blood group)19ReceptorClinical Trials
769
261CYP3A5cytochrome P450 family 3 subfamily A member 57Hub GeneFDA Approved Target
763
262SERPINA1serpin family A member 114Hub GeneOMIM Disease Gene
763
263YBX1Y-box binding protein 11Highly ConstrainedHub Gene
763
264SMARCA4SWI/SNF related BAF chromatin remodeling complex subunit ATPase 419Highly ConstrainedHub Gene
762
265FGFR1fibroblast growth factor receptor 18Highly ConstrainedHub Gene
760
266WT1WT1 transcription factor11Highly ConstrainedHub Gene
759
267CREB1cAMP responsive element binding protein 12Highly ConstrainedHub Gene
757
268ERCC1ERCC excision repair 1, endonuclease non-catalytic subunit19DNA RepairHub Gene
757
269FUSFUS RNA binding protein16Highly ConstrainedHub Gene
757
270IGFBP3insulin like growth factor binding protein 37Highly StudiedExperimental GO Evidence
757
271C3complement C319Hub GeneFDA Approved Target
756
272TLR3toll like receptor 34Hub GeneReceptor
750
273UGT1A1UDP glucuronosyltransferase family 1 member A12Hub GeneOMIM Disease Gene
750
274INSRinsulin receptor19Hub GeneKinase
749
275IGF2insulin like growth factor 211Hub GeneClinical Trials
748
276TWIST1twist family bHLH transcription factor 17OMIM Disease GeneHighly Studied
747
277LEPRleptin receptor1Hub GeneReceptor
746
278APEX1apurinic/apyrimidinic endodeoxyribonuclease 114DNA RepairHub Gene
744
279NAT2N-acetyltransferase 28Highly StudiedExperimental GO Evidence
744
280MECP2methyl-CpG binding protein 2XHighly ConstrainedHub Gene
740
281XRCC6X-ray repair cross complementing 622DNA RepairHighly Constrained
740
282HSPD1heat shock protein family D (Hsp60) member 12Highly ConstrainedHub Gene
739
283IL13interleukin 135Hub GeneFDA Approved Target
739
284BMP2bone morphogenetic protein 220Highly ConstrainedHub Gene
738
285PRKACAprotein kinase cAMP-activated catalytic subunit alpha19Highly ConstrainedHub Gene
737
286HTR2A5-hydroxytryptamine receptor 2A13ReceptorFDA Approved Target
736
287RBX1ring-box 122DNA RepairHub Gene
734
288SCN5Asodium voltage-gated channel alpha subunit 53Hub GeneIon Channel
732
289SMAD2SMAD family member 218Highly ConstrainedHub Gene
732
290IL33interleukin 339Clinical TrialsHighly Studied
730
291TNFSF11TNF superfamily member 1113Hub GeneReceptor
722
292DRD4dopamine receptor D411ReceptorHighly Studied
720
293KMT2Alysine methyltransferase 2A11Highly ConstrainedHub Gene
720
294PRKCDprotein kinase C delta3ApoptosisHighly Constrained
720
295NFKBIANFKB inhibitor alpha14Hub GeneOMIM Disease Gene
719
296BECN1beclin 117Highly ConstrainedHub Gene
716
297CDK4cyclin dependent kinase 412Hub GeneKinase
714
298FGFR2fibroblast growth factor receptor 210Highly ConstrainedHub Gene
713
299CALRcalreticulin19Hub GeneHighly Studied
712
300FLNAfilamin AXHighly ConstrainedHub Gene
712