Most Researched

Genes ranked by total PubMed publication count — the most-studied genes in biology.

Filter by chromosome
Showing 251300 of 20,598 genes
#GeneNameChrTagsPubMedPubMed Papers
251MMP3matrix metallopeptidase 311Hub GeneProtease792792
252CBLCbl proto-oncogene11Hub GeneOncogene785785
253ALBalbumin4Hub GeneOMIM Disease Gene784784
254LPLlipoprotein lipase8Hub GeneOMIM Disease Gene784784
255BCL2L1BCL2 like 120Highly ConstrainedHub Gene780780
256CXCL10C-X-C motif chemokine ligand 104Hub GeneClinical Trials776776
257GJA1gap junction protein alpha 16Hub GeneOMIM Disease Gene773773
258PCSK9proprotein convertase subtilisin/kexin type 91ProteaseFDA Approved Target771771
259TIMP1TIMP metallopeptidase inhibitor 1XHub GeneHighly Studied770770
260BSGbasigin (Ok blood group)19ReceptorClinical Trials769769
261CYP3A5cytochrome P450 family 3 subfamily A member 57Hub GeneFDA Approved Target763763
262SERPINA1serpin family A member 114Hub GeneOMIM Disease Gene763763
263YBX1Y-box binding protein 11Highly ConstrainedHub Gene763763
264SMARCA4SWI/SNF related BAF chromatin remodeling complex subunit ATPase 419Highly ConstrainedHub Gene762762
265FGFR1fibroblast growth factor receptor 18Highly ConstrainedHub Gene760760
266WT1WT1 transcription factor11Highly ConstrainedHub Gene759759
267CREB1cAMP responsive element binding protein 12Highly ConstrainedHub Gene757757
268ERCC1ERCC excision repair 1, endonuclease non-catalytic subunit19DNA RepairHub Gene757757
269FUSFUS RNA binding protein16Highly ConstrainedHub Gene757757
270IGFBP3insulin like growth factor binding protein 37Highly StudiedTrending757757
271C3complement C319Hub GeneFDA Approved Target756756
272TLR3toll like receptor 34Hub GeneReceptor750750
273UGT1A1UDP glucuronosyltransferase family 1 member A12Hub GeneOMIM Disease Gene750750
274INSRinsulin receptor19Hub GeneKinase749749
275IGF2insulin like growth factor 211Hub GeneClinical Trials748748
276TWIST1twist family bHLH transcription factor 17Transcription FactorOMIM Disease Gene747747
277LEPRleptin receptor1Hub GeneReceptor746746
278APEX1apurinic/apyrimidinic endodeoxyribonuclease 114DNA RepairHub Gene744744
279NAT2N-acetyltransferase 28Highly StudiedExperimental GO Evidence744744
280MECP2methyl-CpG binding protein 2XHighly ConstrainedHub Gene740740
281XRCC6X-ray repair cross complementing 622DNA RepairHighly Constrained740740
282HSPD1heat shock protein family D (Hsp60) member 12Highly ConstrainedHub Gene739739
283IL13interleukin 135Hub GeneFDA Approved Target739739
284BMP2bone morphogenetic protein 220Highly ConstrainedHub Gene738738
285PRKACAprotein kinase cAMP-activated catalytic subunit alpha19Highly ConstrainedHub Gene737737
286HTR2A5-hydroxytryptamine receptor 2A13ReceptorFDA Approved Target736736
287RBX1ring-box 122DNA RepairHub Gene734734
288SCN5Asodium voltage-gated channel alpha subunit 53Hub GeneIon Channel732732
289SMAD2SMAD family member 218Highly ConstrainedHub Gene732732
290IL33interleukin 339Clinical TrialsHighly Studied730730
291TNFSF11TNF superfamily member 1113Hub GeneReceptor722722
292DRD4dopamine receptor D411ReceptorHighly Studied720720
293KMT2Alysine methyltransferase 2A11Highly ConstrainedHub Gene720720
294PRKCDprotein kinase C delta3ApoptosisHighly Constrained720720
295NFKBIANFKB inhibitor alpha14Hub GeneOMIM Disease Gene719719
296BECN1beclin 117Highly ConstrainedHub Gene716716
297CDK4cyclin dependent kinase 412Hub GeneKinase714714
298FGFR2fibroblast growth factor receptor 210Highly ConstrainedHub Gene713713
299CALRcalreticulin19Hub GeneHighly Studied712712
300FLNAfilamin AXHighly ConstrainedHub Gene712712