Most Researched

Genes ranked by total PubMed publication count — the most-studied genes in biology.

Filter by chromosome
Showing 351400 of 20,598 genes
#GeneNameChrTagsPubMedPubMed Papers
351ATRATR checkpoint kinase3DNA RepairHub Gene641641
352RUNX2RUNX family transcription factor 26Hub GeneTranscription Factor641641
353KCNQ1potassium voltage-gated channel subfamily Q member 111Ion ChannelTransporter639639
354APOBEC3Gapolipoprotein B mRNA editing enzyme catalytic subunit 3G22Highly StudiedExperimental GO Evidence637637
355NF1neurofibromin 117Hub GeneTumor Suppressor637637
356EPAS1endothelial PAS domain protein 12Transcription FactorFDA Approved Target636636
357SUMO1small ubiquitin like modifier 12Hub GeneOMIM Disease Gene636636
358XPO1exportin 12Highly ConstrainedHub Gene635635
359PROM1prominin 14OMIM Disease GeneHighly Studied631631
360HSP90AB1heat shock protein 90 alpha family class B member 16Hub GeneClinical Trials629629
361THBS1thrombospondin 115Highly ConstrainedHub Gene629629
362TYMSthymidylate synthetase18Hub GeneFDA Approved Target629629
363HNRNPKheterogeneous nuclear ribonucleoprotein K9Highly ConstrainedHub Gene628628
364RACK1receptor for activated C kinase 15Highly ConstrainedHub Gene628628
365CALM1calmodulin 114Hub GeneFDA Approved Target627627
366C9orf72C9orf72-SMCR8 complex subunit9OMIM Disease GeneHighly Studied626626
367CD40CD40 molecule20Hub GeneReceptor626626
368MYD88MYD88 innate immune signal transduction adaptor3ApoptosisHub Gene624624
369UBE2D1ubiquitin conjugating enzyme E2 D110Hub GeneHighly Studied624624
370GAPDHglyceraldehyde-3-phosphate dehydrogenase12Hub GeneHighly Studied623623
371RIGIRNA sensor RIG-I9OMIM Disease GeneHighly Studied621621
372VCAM1vascular cell adhesion molecule 11Hub GeneHighly Studied621621
373OPRM1opioid receptor mu 16ReceptorFDA Approved Target620620
374DPP4dipeptidyl peptidase 42Hub GeneProtease619619
375TGFBR2transforming growth factor beta receptor 23ApoptosisHub Gene617617
376CHEK1checkpoint kinase 111DNA RepairHub Gene616616
377FBXW7F-box and WD repeat domain containing 74DNA RepairHighly Constrained616616
378FGFR3fibroblast growth factor receptor 34Hub GeneKinase616616
379SKP1S-phase kinase associated protein 15Highly ConstrainedHub Gene616616
380DNMT3ADNA methyltransferase 3 alpha2Hub GeneFDA Approved Target613613
381TGFBR1transforming growth factor beta receptor 19Hub GeneKinase612612
382YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon17Highly ConstrainedHub Gene612612
383CCN2cellular communication network factor 26Hub GeneClinical Trials611611
384GRNgranulin precursor17OMIM Disease GeneHighly Studied611611
385FASNfatty acid synthase17Highly ConstrainedHub Gene610610
386MMP14matrix metallopeptidase 1414Highly ConstrainedProtease609609
387BMI1BMI1 proto-oncogene, polycomb ring finger10Hub GeneOncogene606606
388UBE2Iubiquitin conjugating enzyme E2 I16Highly ConstrainedHub Gene606606
389SHHsonic hedgehog signaling molecule7Hub GeneProtease605605
390NBNnibrin8DNA RepairHomologous Recombination604604
391SKP2S-phase kinase associated protein 25Hub GeneHighly Studied604604
392HNRNPA1heterogeneous nuclear ribonucleoprotein A112Hub GeneTransporter602602
393IFNL3interferon lambda 319Highly StudiedExperimental GO Evidence601601
394IL12Binterleukin 12B5FDA Approved TargetOMIM Disease Gene601601
395CCNB1cyclin B15Hub GeneHighly Studied599599
396TRIM28tripartite motif containing 2819DNA RepairHighly Constrained599599
397LTAlymphotoxin alpha6OMIM Disease GeneHighly Studied598598
398PLAUplasminogen activator, urokinase10ProteaseFDA Approved Target596596
399HNF4Ahepatocyte nuclear factor 4 alpha20Hub GeneReceptor592592
400TRAF2TNF receptor associated factor 29Highly ConstrainedHub Gene592592