Most Researched

Genes ranked by total PubMed publication count — the most-studied genes in biology.

Filter by chromosome
351400 of 20,598 genesranked by Most Researched
#GeneNameChrTagsPubMed Papers
351ATRATR checkpoint kinase3DNA RepairHub Gene
641
352RUNX2RUNX family transcription factor 26Hub GeneOMIM Disease Gene
641
353KCNQ1potassium voltage-gated channel subfamily Q member 111Ion ChannelTransporter
639
354APOBEC3Gapolipoprotein B mRNA editing enzyme catalytic subunit 3G22Highly StudiedExperimental GO Evidence
637
355NF1neurofibromin 117Hub GeneTumor Suppressor
637
356EPAS1endothelial PAS domain protein 12FDA Approved TargetOMIM Disease Gene
636
357SUMO1small ubiquitin like modifier 12Hub GeneOMIM Disease Gene
636
358XPO1exportin 12Highly ConstrainedHub Gene
635
359PROM1prominin 14OMIM Disease GeneHighly Studied
631
360HSP90AB1heat shock protein 90 alpha family class B member 16Hub GeneClinical Trials
629
361THBS1thrombospondin 115Highly ConstrainedHub Gene
629
362TYMSthymidylate synthetase18Hub GeneFDA Approved Target
629
363HNRNPKheterogeneous nuclear ribonucleoprotein K9Highly ConstrainedHub Gene
628
364RACK1receptor for activated C kinase 15Highly ConstrainedHub Gene
628
365CALM1calmodulin 114Hub GeneFDA Approved Target
627
366C9orf72C9orf72-SMCR8 complex subunit9OMIM Disease GeneHighly Studied
626
367CD40CD40 molecule20Hub GeneReceptor
626
368MYD88MYD88 innate immune signal transduction adaptor3ApoptosisHub Gene
624
369UBE2D1ubiquitin conjugating enzyme E2 D110Hub GeneHighly Studied
624
370GAPDHglyceraldehyde-3-phosphate dehydrogenase12Hub GeneHighly Studied
623
371RIGIRNA sensor RIG-I9OMIM Disease GeneHighly Studied
621
372VCAM1vascular cell adhesion molecule 11Hub GeneHighly Studied
621
373OPRM1opioid receptor mu 16ReceptorFDA Approved Target
620
374DPP4dipeptidyl peptidase 42Hub GeneProtease
619
375TGFBR2transforming growth factor beta receptor 23ApoptosisHub Gene
617
376CHEK1checkpoint kinase 111DNA RepairHub Gene
616
377FBXW7F-box and WD repeat domain containing 74DNA RepairHighly Constrained
616
378FGFR3fibroblast growth factor receptor 34Hub GeneKinase
616
379SKP1S-phase kinase associated protein 15Highly ConstrainedHub Gene
616
380DNMT3ADNA methyltransferase 3 alpha2Hub GeneFDA Approved Target
613
381TGFBR1transforming growth factor beta receptor 19Hub GeneKinase
612
382YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon17Highly ConstrainedHub Gene
612
383CCN2cellular communication network factor 26Hub GeneClinical Trials
611
384GRNgranulin precursor17OMIM Disease GeneHighly Studied
611
385FASNfatty acid synthase17Highly ConstrainedHub Gene
610
386MMP14matrix metallopeptidase 1414Highly ConstrainedProtease
609
387BMI1BMI1 proto-oncogene, polycomb ring finger10Hub GeneOncogene
606
388UBE2Iubiquitin conjugating enzyme E2 I16Highly ConstrainedHub Gene
606
389SHHsonic hedgehog signaling molecule7Hub GeneProtease
605
390NBNnibrin8DNA RepairHomologous Recombination
604
391SKP2S-phase kinase associated protein 25Hub GeneHighly Studied
604
392HNRNPA1heterogeneous nuclear ribonucleoprotein A112Hub GeneTransporter
602
393IFNL3interferon lambda 319Highly StudiedExperimental GO Evidence
601
394IL12Binterleukin 12B5FDA Approved TargetOMIM Disease Gene
601
395CCNB1cyclin B15Hub GeneHighly Studied
599
396TRIM28tripartite motif containing 2819DNA RepairHighly Constrained
599
397LTAlymphotoxin alpha6OMIM Disease GeneHighly Studied
598
398PLAUplasminogen activator, urokinase10ProteaseFDA Approved Target
596
399HNF4Ahepatocyte nuclear factor 4 alpha20Hub GeneReceptor
592
400TRAF2TNF receptor associated factor 29Highly ConstrainedHub Gene
592