Most Researched

Genes ranked by total PubMed publication count — the most-studied genes in biology.

Filter by chromosome
351400 of 20,598 genesranked by Most Researched
#GeneNameChrTagsPubMed Papers
351ATRATR checkpoint kinase3DNA RepairKinase
641
352RUNX2RUNX family transcription factor 26OMIM Disease GeneHighly Studied
641
353KCNQ1potassium voltage-gated channel subfamily Q member 111Ion ChannelTransporter
639
354APOBEC3Gapolipoprotein B mRNA editing enzyme catalytic subunit 3G22Highly StudiedExperimental GO Evidence
637
355NF1neurofibromin 117Tumor SuppressorOMIM Disease Gene
637
356EPAS1endothelial PAS domain protein 12FDA Approved TargetOMIM Disease Gene
636
357SUMO1small ubiquitin like modifier 12OMIM Disease GeneHighly Studied
636
358XPO1exportin 12Highly ConstrainedTransporter
635
359PROM1prominin 14OMIM Disease GeneHighly Studied
631
360HSP90AB1heat shock protein 90 alpha family class B member 16Clinical TrialsHighly Studied
629
361THBS1thrombospondin 115Highly ConstrainedHighly Studied
629
362TYMSthymidylate synthetase18FDA Approved TargetOMIM Disease Gene
629
363HNRNPKheterogeneous nuclear ribonucleoprotein K9Highly ConstrainedOMIM Disease Gene
628
364RACK1receptor for activated C kinase 15Highly ConstrainedHighly Studied
628
365CALM1calmodulin 114FDA Approved TargetHighly Studied
627
366C9orf72C9orf72-SMCR8 complex subunit9OMIM Disease GeneHighly Studied
626
367CD40CD40 molecule20ReceptorClinical Trials
626
368MYD88MYD88 innate immune signal transduction adaptor3ApoptosisOMIM Disease Gene
624
369UBE2D1ubiquitin conjugating enzyme E2 D110Highly StudiedExperimental GO Evidence
624
370GAPDHglyceraldehyde-3-phosphate dehydrogenase12Highly StudiedExperimental GO Evidence
623
371RIGIRNA sensor RIG-I9OMIM Disease GeneHighly Studied
621
372VCAM1vascular cell adhesion molecule 11Highly StudiedExperimental GO Evidence
621
373OPRM1opioid receptor mu 16ReceptorFDA Approved Target
620
374DPP4dipeptidyl peptidase 42ProteaseReceptor
619
375TGFBR2transforming growth factor beta receptor 23ApoptosisKinase
617
376CHEK1checkpoint kinase 111DNA RepairKinase
616
377FBXW7F-box and WD repeat domain containing 74DNA RepairHighly Constrained
616
378FGFR3fibroblast growth factor receptor 34KinaseReceptor
616
379SKP1S-phase kinase associated protein 15Highly ConstrainedHighly Studied
616
380DNMT3ADNA methyltransferase 3 alpha2FDA Approved TargetOMIM Disease Gene
613
381TGFBR1transforming growth factor beta receptor 19KinaseReceptor
612
382YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon17Highly ConstrainedHighly Studied
612
383CCN2cellular communication network factor 26Clinical TrialsOMIM Disease Gene
611
384GRNgranulin precursor17OMIM Disease GeneHighly Studied
611
385FASNfatty acid synthase17Highly ConstrainedHighly Studied
610
386MMP14matrix metallopeptidase 1414Highly ConstrainedProtease
609
387BMI1BMI1 proto-oncogene, polycomb ring finger10OncogeneHighly Studied
606
388UBE2Iubiquitin conjugating enzyme E2 I16Highly ConstrainedHighly Studied
606
389SHHsonic hedgehog signaling molecule7ProteaseOMIM Disease Gene
605
390NBNnibrin8DNA RepairHomologous Recombination
604
391SKP2S-phase kinase associated protein 25Highly StudiedExperimental GO Evidence
604
392HNRNPA1heterogeneous nuclear ribonucleoprotein A112TransporterOMIM Disease Gene
602
393IFNL3interferon lambda 319Highly StudiedExperimental GO Evidence
601
394IL12Binterleukin 12B5FDA Approved TargetOMIM Disease Gene
601
395CCNB1cyclin B15Highly StudiedExperimental GO Evidence
599
396TRIM28tripartite motif containing 2819DNA RepairHighly Constrained
599
397LTAlymphotoxin alpha6OMIM Disease GeneHighly Studied
598
398PLAUplasminogen activator, urokinase10ProteaseFDA Approved Target
596
399HNF4Ahepatocyte nuclear factor 4 alpha20ReceptorTranscription Factor
592
400TRAF2TNF receptor associated factor 29Highly ConstrainedHighly Studied
592