Most Researched

Genes ranked by total PubMed publication count — the most-studied genes in biology.

Filter by chromosome
401–450 of 20,598 genesranked by Most Researched
#GeneNameChrTagsPubMed Papers
401CYP1B1cytochrome P450 family 1 subfamily B member 12Hub GeneOMIM Disease Gene
591
402SHC1SHC adaptor protein 11Hub GeneHighly Studied
591
403CYP17A1cytochrome P450 family 17 subfamily A member 110FDA Approved TargetOMIM Disease Gene
590
404PTPN22protein tyrosine phosphatase non-receptor type 221OMIM Disease GeneHighly Studied
589
405TFRCtransferrin receptor3Hub GeneReceptor
589
406DMDdystrophinXHighly ConstrainedHub Gene
588
407SYKspleen associated tyrosine kinase9Highly ConstrainedHub Gene
587
408AGO2argonaute RISC catalytic component 28Highly ConstrainedHub Gene
585
409STK11serine/threonine kinase 1119Hub GeneKinase
585
410KPNB1karyopherin subunit beta 117Highly ConstrainedHub Gene
580
411H2AXH2A.X variant histone11DNA RepairHub Gene
579
412ERBB3erb-b2 receptor tyrosine kinase 312Hub GeneKinase
575
413H3C1H3 clustered histone 16Hub GeneHighly Studied
575
414IL2RAinterleukin 2 receptor subunit alpha10Hub GeneReceptor
575
415YWHAQtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta2Hub GeneHighly Studied
575
416CHI3L1chitinase 3 like 11OMIM Disease GeneHighly Studied
574
417CDK9cyclin dependent kinase 99DNA RepairHub Gene
573
418PAK1p21 (RAC1) activated kinase 111KinaseOMIM Disease Gene
573
419NRG1neuregulin 18Highly StudiedExperimental GO Evidence
570
420PARK7Parkinsonism associated deglycase1DNA RepairHub Gene
570
421CHUKcomponent of inhibitor of nuclear factor kappa B kinase complex10Hub GeneKinase
568
422SOX9SRY-box transcription factor 917Highly ConstrainedTranscription Factor
567
423ITGB2integrin subunit beta 221Hub GeneReceptor
566
424KDM1Alysine demethylase 1A1Hub GeneClinical Trials
566
425PDGFRBplatelet derived growth factor receptor beta5Hub GeneKinase
565
426LCKLCK proto-oncogene, Src family tyrosine kinase1Highly ConstrainedHub Gene
564
427RANRAN, member RAS oncogene family12Highly ConstrainedHub Gene
564
428BTRCbeta-transducin repeat containing E3 ubiquitin protein ligase10Hub GeneHighly Studied
563
429MICAMHC class I polypeptide-related sequence A6OMIM Disease GeneHighly Studied
563
430LGALS1galectin 122Early PipelineHighly Studied
562
431AURKBaurora kinase B17Hub GeneKinase
561
432TBK1TANK binding kinase 112Hub GeneKinase
561
433G6PDglucose-6-phosphate dehydrogenaseXHighly ConstrainedHub Gene
560
434IKBKGinhibitor of nuclear factor kappa B kinase regulatory subunit gammaXHub GeneOMIM Disease Gene
560
435UBE2D3ubiquitin conjugating enzyme E2 D34DNA RepairHighly Constrained
560
436EEF1A1eukaryotic translation elongation factor 1 alpha 16Highly ConstrainedHub Gene
559
437PDGFRAplatelet derived growth factor receptor alpha4Highly ConstrainedHub Gene
558
438HSPA9heat shock protein family A (Hsp70) member 95Hub GeneOMIM Disease Gene
557
439YY1YY1 transcription factor14DNA RepairHighly Constrained
557
440EGR1early growth response 15Transcription FactorClinical Trials
555
441CCR2C-C motif chemokine receptor 23Hub GeneReceptor
553
442CEBPACCAAT enhancer binding protein alpha19Hub GeneTranscription Factor
553
443KPNA2karyopherin subunit alpha 217Hub GeneTransporter
553
444SOCS3suppressor of cytokine signaling 317Hub GeneHighly Studied
553
445STIM1stromal interaction molecule 111TransporterOMIM Disease Gene
552
446TNFRSF1BTNF receptor superfamily member 1B1ReceptorHighly Studied
552
447UBE2D2ubiquitin conjugating enzyme E2 D25Highly ConstrainedHub Gene
551
448DDX3XDEAD-box helicase 3 X-linkedXHighly ConstrainedHub Gene
550
449DHX9DExH-box helicase 91Highly ConstrainedHub Gene
550
450ROCK1Rho associated coiled-coil containing protein kinase 118Highly ConstrainedHub Gene
549