401–450 of 20,598 genesranked by Most Researched

#	Gene	Name	Chr	Tags	PubMed Papers
401	CYP1B1	cytochrome P450 family 1 subfamily B member 1	2	OMIM Disease GeneHighly Studied	591
402	SHC1	SHC adaptor protein 1	1	Highly StudiedExperimental GO Evidence	591
403	CYP17A1	cytochrome P450 family 17 subfamily A member 1	10	FDA Approved TargetOMIM Disease Gene	590
404	PTPN22	protein tyrosine phosphatase non-receptor type 22	1	OMIM Disease GeneHighly Studied	589
405	TFRC	transferrin receptor	3	ReceptorFDA Approved Target	589
406	DMD	dystrophin	X	Highly ConstrainedFDA Approved Target	588
407	SYK	spleen associated tyrosine kinase	9	Highly ConstrainedKinase	587
408	AGO2	argonaute RISC catalytic component 2	8	Highly ConstrainedOMIM Disease Gene	585
409	STK11	serine/threonine kinase 11	19	KinaseTumor Suppressor	585
410	KPNB1	karyopherin subunit beta 1	17	Highly ConstrainedTransporter	580
411	H2AX	H2A.X variant histone	11	DNA RepairHighly Studied	579
412	ERBB3	erb-b2 receptor tyrosine kinase 3	12	KinaseReceptor	575
413	H3C1	H3 clustered histone 1	6	Highly StudiedExperimental GO Evidence	575
414	IL2RA	interleukin 2 receptor subunit alpha	10	ReceptorFDA Approved Target	575
415	YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta	2	Highly StudiedExperimental GO Evidence	575
416	CHI3L1	chitinase 3 like 1	1	OMIM Disease GeneHighly Studied	574
417	CDK9	cyclin dependent kinase 9	9	DNA RepairKinase	573
418	PAK1	p21 (RAC1) activated kinase 1	11	KinaseOMIM Disease Gene	573
419	NRG1	neuregulin 1	8	Highly StudiedExperimental GO Evidence	570
420	PARK7	Parkinsonism associated deglycase	1	DNA RepairProtease	570
421	CHUK	component of inhibitor of nuclear factor kappa B kinase complex	10	KinaseOMIM Disease Gene	568
422	SOX9	SRY-box transcription factor 9	17	Highly ConstrainedTranscription Factor	567
423	ITGB2	integrin subunit beta 2	21	ReceptorFDA Approved Target	566
424	KDM1A	lysine demethylase 1A	1	Clinical TrialsOMIM Disease Gene	566
425	PDGFRB	platelet derived growth factor receptor beta	5	KinaseOncogene	565
426	LCK	LCK proto-oncogene, Src family tyrosine kinase	1	Highly ConstrainedKinase	564
427	RAN	RAN, member RAS oncogene family	12	Highly ConstrainedTransporter	564
428	BTRC	beta-transducin repeat containing E3 ubiquitin protein ligase	10	Highly StudiedExperimental GO Evidence	563
429	MICA	MHC class I polypeptide-related sequence A	6	OMIM Disease GeneHighly Studied	563
430	LGALS1	galectin 1	22	Clinical TrialsHighly Studied	562
431	AURKB	aurora kinase B	17	KinaseClinical Trials	561
432	TBK1	TANK binding kinase 1	12	KinaseOMIM Disease Gene	561
433	G6PD	glucose-6-phosphate dehydrogenase	X	Highly ConstrainedOMIM Disease Gene	560
434	IKBKG	inhibitor of nuclear factor kappa B kinase regulatory subunit gamma	X	OMIM Disease GeneHighly Studied	560
435	UBE2D3	ubiquitin conjugating enzyme E2 D3	4	DNA RepairHighly Constrained	560
436	EEF1A1	eukaryotic translation elongation factor 1 alpha 1	6	Highly ConstrainedHighly Studied	559
437	PDGFRA	platelet derived growth factor receptor alpha	4	Highly ConstrainedKinase	558
438	HSPA9	heat shock protein family A (Hsp70) member 9	5	OMIM Disease GeneHighly Studied	557
439	YY1	YY1 transcription factor	14	DNA RepairHighly Constrained	557
440	EGR1	early growth response 1	5	Transcription FactorClinical Trials	555
441	CCR2	C-C motif chemokine receptor 2	3	ReceptorClinical Trials	553
442	CEBPA	CCAAT enhancer binding protein alpha	19	Transcription FactorOMIM Disease Gene	553
443	KPNA2	karyopherin subunit alpha 2	17	TransporterHighly Studied	553
444	SOCS3	suppressor of cytokine signaling 3	17	Highly StudiedExperimental GO Evidence	553
445	STIM1	stromal interaction molecule 1	11	TransporterOMIM Disease Gene	552
446	TNFRSF1B	TNF receptor superfamily member 1B	1	ReceptorHighly Studied	552
447	UBE2D2	ubiquitin conjugating enzyme E2 D2	5	Highly ConstrainedHighly Studied	551
448	DDX3X	DEAD-box helicase 3 X-linked	X	Highly ConstrainedOMIM Disease Gene	550
449	DHX9	DExH-box helicase 9	1	Highly ConstrainedTransporter	550
450	ROCK1	Rho associated coiled-coil containing protein kinase 1	18	Highly ConstrainedKinase	549