Most Researched

Genes ranked by total PubMed publication count — the most-studied genes in biology.

Filter by chromosome
Showing 401450 of 20,598 genes
#GeneNameChrTagsPubMedPubMed Papers
401CYP1B1cytochrome P450 family 1 subfamily B member 12Hub GeneOMIM Disease Gene591591
402SHC1SHC adaptor protein 11Hub GeneHighly Studied591591
403CYP17A1cytochrome P450 family 17 subfamily A member 110FDA Approved TargetOMIM Disease Gene590590
404PTPN22protein tyrosine phosphatase non-receptor type 221OMIM Disease GeneHighly Studied589589
405TFRCtransferrin receptor3Hub GeneReceptor589589
406DMDdystrophinXHighly ConstrainedHub Gene588588
407SYKspleen associated tyrosine kinase9Highly ConstrainedHub Gene587587
408AGO2argonaute RISC catalytic component 28Highly ConstrainedHub Gene585585
409STK11serine/threonine kinase 1119Hub GeneKinase585585
410KPNB1karyopherin subunit beta 117Highly ConstrainedHub Gene580580
411H2AXH2A.X variant histone11DNA RepairHub Gene579579
412ERBB3erb-b2 receptor tyrosine kinase 312Hub GeneKinase575575
413H3C1H3 clustered histone 16Hub GeneHighly Studied575575
414IL2RAinterleukin 2 receptor subunit alpha10Hub GeneReceptor575575
415YWHAQtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta2Hub GeneHighly Studied575575
416CHI3L1chitinase 3 like 11OMIM Disease GeneHighly Studied574574
417CDK9cyclin dependent kinase 99DNA RepairHub Gene573573
418PAK1p21 (RAC1) activated kinase 111KinaseOMIM Disease Gene573573
419NRG1neuregulin 18Highly StudiedTrending570570
420PARK7Parkinsonism associated deglycase1DNA RepairHub Gene570570
421CHUKcomponent of inhibitor of nuclear factor kappa B kinase complex10Hub GeneKinase568568
422SOX9SRY-box transcription factor 917Highly ConstrainedTranscription Factor567567
423ITGB2integrin subunit beta 221Hub GeneReceptor566566
424KDM1Alysine demethylase 1A1Hub GeneTranscription Factor566566
425PDGFRBplatelet derived growth factor receptor beta5Hub GeneKinase565565
426LCKLCK proto-oncogene, Src family tyrosine kinase1Highly ConstrainedHub Gene564564
427RANRAN, member RAS oncogene family12Highly ConstrainedHub Gene564564
428BTRCbeta-transducin repeat containing E3 ubiquitin protein ligase10Hub GeneHighly Studied563563
429MICAMHC class I polypeptide-related sequence A6OMIM Disease GeneHighly Studied563563
430LGALS1galectin 122Early PipelineHighly Studied562562
431AURKBaurora kinase B17Hub GeneKinase561561
432TBK1TANK binding kinase 112Hub GeneKinase561561
433G6PDglucose-6-phosphate dehydrogenaseXHighly ConstrainedHub Gene560560
434IKBKGinhibitor of nuclear factor kappa B kinase regulatory subunit gammaXHub GeneTranscription Factor560560
435UBE2D3ubiquitin conjugating enzyme E2 D34DNA RepairHighly Constrained560560
436EEF1A1eukaryotic translation elongation factor 1 alpha 16Highly ConstrainedHub Gene559559
437PDGFRAplatelet derived growth factor receptor alpha4Highly ConstrainedHub Gene558558
438HSPA9heat shock protein family A (Hsp70) member 95Hub GeneOMIM Disease Gene557557
439YY1YY1 transcription factor14DNA RepairHighly Constrained557557
440EGR1early growth response 15Transcription FactorClinical Trials555555
441CCR2C-C motif chemokine receptor 23Hub GeneReceptor553553
442CEBPACCAAT enhancer binding protein alpha19Hub GeneTranscription Factor553553
443KPNA2karyopherin subunit alpha 217Hub GeneTransporter553553
444SOCS3suppressor of cytokine signaling 317Hub GeneHighly Studied553553
445STIM1stromal interaction molecule 111TransporterOMIM Disease Gene552552
446TNFRSF1BTNF receptor superfamily member 1B1ReceptorHighly Studied552552
447UBE2D2ubiquitin conjugating enzyme E2 D25Highly ConstrainedHub Gene551551
448DDX3XDEAD-box helicase 3 X-linkedXHighly ConstrainedHub Gene550550
449DHX9DExH-box helicase 91Highly ConstrainedHub Gene550550
450ROCK1Rho associated coiled-coil containing protein kinase 118Highly ConstrainedHub Gene549549