451–500 of 20,598 genesranked by Most Researched
| # | Gene | Name | Chr | Tags | PubMed Papers |
|---|---|---|---|---|---|
| 451 | TGM2 | transglutaminase 2 | 20 | ProteaseHighly Studied | 549 |
| 452 | CD40LG | CD40 ligand | X | Highly ConstrainedHub Gene | 548 |
| 453 | P2RX7 | purinergic receptor P2X 7 | 12 | Ion ChannelReceptor | 547 |
| 454 | RIPK1 | receptor interacting serine/threonine kinase 1 | 6 | ApoptosisHub Gene | 547 |
| 455 | CD36 | CD36 molecule (CD36 blood group) | 7 | Hub GeneReceptor | 546 |
| 456 | GBA1 | glucosylceramidase beta 1 | 1 | Clinical TrialsOMIM Disease Gene | 545 |
| 457 | HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 7 | Highly ConstrainedHub Gene | 544 |
| 458 | CALCA | calcitonin related polypeptide alpha | 11 | FDA Approved TargetHighly Studied | 542 |
| 459 | KLF4 | KLF transcription factor 4 | 9 | Transcription FactorHighly Studied | 542 |
| 460 | ADAM17 | ADAM metallopeptidase domain 17 | 2 | ProteaseClinical Trials | 541 |
| 461 | CLTC | clathrin heavy chain | 17 | Highly ConstrainedHub Gene | 540 |
| 462 | HNF1A | HNF1 homeobox A | 12 | Transcription FactorOMIM Disease Gene | 540 |
| 463 | ADAMTS13 | ADAM metallopeptidase with thrombospondin type 1 motif 13 | 9 | ProteaseOMIM Disease Gene | 539 |
| 464 | TSC2 | TSC complex subunit 2 | 16 | Highly ConstrainedHub Gene | 539 |
| 465 | MSH6 | mutS homolog 6 | 2 | DNA RepairHub Gene | 538 |
| 466 | TNFAIP3 | TNF alpha induced protein 3 | 6 | Highly ConstrainedHub Gene | 538 |
| 467 | TXN | thioredoxin | 9 | Hub GeneTransporter | 538 |
| 468 | MAP3K7 | mitogen-activated protein kinase kinase kinase 7 | 6 | Hub GeneKinase | 537 |
| 469 | CASR | calcium sensing receptor | 3 | ReceptorFDA Approved Target | 535 |
| 470 | HMGA2 | high mobility group AT-hook 2 | 12 | OncogeneOMIM Disease Gene | 535 |
| 471 | LRP1 | LDL receptor related protein 1 | 12 | Highly ConstrainedReceptor | 535 |
| 472 | FCGR2A | Fc gamma receptor IIa | 1 | ReceptorHighly Studied | 534 |
| 473 | DKK1 | dickkopf Wnt signaling pathway inhibitor 1 | 10 | Clinical TrialsHighly Studied | 533 |
| 474 | ENG | endoglin | 9 | Hub GeneClinical Trials | 533 |
| 475 | FOS | Fos proto-oncogene, AP-1 transcription factor subunit | 14 | Hub GeneOncogene | 532 |
| 476 | SF3B1 | splicing factor 3b subunit 1 | 2 | Highly ConstrainedHub Gene | 532 |
| 477 | ANGPT2 | angiopoietin 2 | 8 | FDA Approved TargetOMIM Disease Gene | 531 |
| 478 | EIF2AK2 | eukaryotic translation initiation factor 2 alpha kinase 2 | 2 | Hub GeneKinase | 531 |
| 479 | PABPC1 | poly(A) binding protein cytoplasmic 1 | 8 | Highly ConstrainedHub Gene | 531 |
| 480 | KL | klotho | 13 | OMIM Disease GeneHighly Studied | 529 |
| 481 | PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 | 19 | Highly StudiedExperimental GO Evidence | 529 |
| 482 | SMARCB1 | SWI/SNF related BAF chromatin remodeling complex subunit B1 | 22 | Highly ConstrainedHub Gene | 529 |
| 483 | CNR1 | cannabinoid receptor 1 | 6 | ReceptorFDA Approved Target | 528 |
| 484 | IRF3 | interferon regulatory factor 3 | 19 | Hub GeneTranscription Factor | 528 |
| 485 | JAK1 | Janus kinase 1 | 1 | Highly ConstrainedHub Gene | 528 |
| 486 | S100A8 | S100 calcium binding protein A8 | 1 | Highly StudiedTrending | 528 |
| 487 | TOP1 | DNA topoisomerase I | 20 | Highly ConstrainedOncogene | 528 |
| 488 | ENO1 | enolase 1 | 1 | Hub GeneHighly Studied | 526 |
| 489 | HSP90B1 | heat shock protein 90 beta family member 1 | 12 | Highly ConstrainedHub Gene | 526 |
| 490 | ADAR | adenosine deaminase RNA specific | 1 | OMIM Disease GeneHighly Studied | 525 |
| 491 | LDHA | lactate dehydrogenase A | 11 | Hub GeneOMIM Disease Gene | 525 |
| 492 | PRMT5 | protein arginine methyltransferase 5 | 14 | Highly ConstrainedHub Gene | 525 |
| 493 | RPA1 | replication protein A1 | 17 | DNA RepairHomologous Recombination | 525 |
| 494 | FBN1 | fibrillin 1 | 15 | Highly ConstrainedHub Gene | 523 |
| 495 | HNRNPU | heterogeneous nuclear ribonucleoprotein U | 1 | Highly ConstrainedHub Gene | 523 |
| 496 | MAP2K1 | mitogen-activated protein kinase kinase 1 | 15 | Hub GeneKinase | 523 |
| 497 | CCNE1 | cyclin E1 | 19 | Highly StudiedTrending | 522 |
| 498 | CEBPB | CCAAT enhancer binding protein beta | 20 | Hub GeneHighly Studied | 522 |
| 499 | DDX5 | DEAD-box helicase 5 | 17 | Highly ConstrainedHub Gene | 522 |
| 500 | MRE11 | MRE11 double strand break repair nuclease | 11 | DNA RepairHomologous Recombination | 522 |