501–550 of 20,598 genesranked by Most Researched

#	Gene	Name	Chr	Tags	PubMed Papers
501	TIMP2	TIMP metallopeptidase inhibitor 2	17	Highly StudiedExperimental GO Evidence	522
502	XRCC3	X-ray repair cross complementing 3	14	DNA RepairHomologous Recombination	520
503	HDAC6	histone deacetylase 6	X	Highly ConstrainedFDA Approved Target	519
504	RASSF1	Ras association domain family member 1	3	Tumor SuppressorHighly Studied	519
505	PPP2CA	protein phosphatase 2 catalytic subunit alpha	5	Highly ConstrainedClinical Trials	518
506	BCL2L11	BCL2 like 11	2	Highly StudiedExperimental GO Evidence	517
507	IL6R	interleukin 6 receptor	1	ReceptorFDA Approved Target	517
508	BRD4	bromodomain containing 4	19	Highly ConstrainedFDA Approved Target	516
509	TUBB	tubulin beta class I	6	Highly ConstrainedOMIM Disease Gene	516
510	GATA3	GATA binding protein 3	10	Transcription FactorOMIM Disease Gene	515
511	IDH2	isocitrate dehydrogenase (NADP(+)) 2	15	FDA Approved TargetOMIM Disease Gene	515
512	RXRA	retinoid X receptor alpha	9	Highly ConstrainedReceptor	515
513	IDO1	indoleamine 2,3-dioxygenase 1	8	FDA Approved TargetHighly Studied	514
514	LPA	lipoprotein(a)	6	ProteaseTransporter	514
515	BMP4	bone morphogenetic protein 4	14	Highly ConstrainedOMIM Disease Gene	513
516	EIF4E	eukaryotic translation initiation factor 4E	4	Highly ConstrainedTransporter	513
517	MMP7	matrix metallopeptidase 7	11	ProteaseFDA Approved Target	513
518	CYP1A2	cytochrome P450 family 1 subfamily A member 2	15	Highly StudiedExperimental GO Evidence	511
519	MYCN	MYCN proto-oncogene, bHLH transcription factor	2	Highly ConstrainedOncogene	511
520	PINK1	PTEN induced kinase 1	1	KinaseOMIM Disease Gene	510
521	SRSF1	serine and arginine rich splicing factor 1	17	Highly ConstrainedTransporter	510
522	HDAC3	histone deacetylase 3	5	FDA Approved TargetHighly Studied	509
523	NOTCH3	notch receptor 3	19	ReceptorClinical Trials	508
524	STING1	stimulator of interferon response cGAMP interactor 1	5	Ion ChannelTransporter	508
525	ANXA1	annexin A1	9	Highly StudiedTrending	507
526	EWSR1	EWS RNA binding protein 1	22	Highly ConstrainedOncogene	507
527	IL15	interleukin 15	4	Clinical TrialsHighly Studied	506
528	S100B	S100 calcium binding protein B	21	Highly StudiedExperimental GO Evidence	506
529	YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta	20	Highly ConstrainedHighly Studied	505
530	BCR	BCR activator of RhoGEF and GTPase	22	KinaseOncogene	502
531	TNFSF13B	TNF superfamily member 13b	13	FDA Approved TargetHighly Studied	502
532	IGF2BP3	insulin like growth factor 2 mRNA binding protein 3	7	Highly ConstrainedTransporter	501
533	ITGA5	integrin subunit alpha 5	12	ReceptorClinical Trials	501
534	CFL1	cofilin 1	11	Highly StudiedExperimental GO Evidence	499
535	PTBP1	polypyrimidine tract binding protein 1	19	Highly ConstrainedHighly Studied	499
536	VEGFC	vascular endothelial growth factor C	4	Clinical TrialsOMIM Disease Gene	497
537	ARID1A	AT-rich interaction domain 1A	1	Highly ConstrainedOMIM Disease Gene	494
538	MC4R	melanocortin 4 receptor	18	ReceptorFDA Approved Target	494
539	PTX3	pentraxin 3	3	Highly StudiedTrending	494
540	DNMT3B	DNA methyltransferase 3 beta	20	OMIM Disease GeneHighly Studied	492
541	FCGR3A	Fc gamma receptor IIIa	1	ReceptorClinical Trials	492
542	ERG	ETS transcription factor ERG	21	Highly ConstrainedOncogene	491
543	PRDX1	peroxiredoxin 1	1	Highly StudiedTrending	491
544	MTR	5-methyltetrahydrofolate-homocysteine methyltransferase	1	OMIM Disease GeneHighly Studied	489
545	CAT	catalase	11	OMIM Disease GeneHighly Studied	488
546	PTPN1	protein tyrosine phosphatase non-receptor type 1	20	Highly ConstrainedHighly Studied	488
547	SOCS1	suppressor of cytokine signaling 1	16	OMIM Disease GeneHighly Studied	486
548	F7	coagulation factor VII	13	ProteaseFDA Approved Target	485
549	B2M	beta-2-microglobulin	15	OMIM Disease GeneHighly Studied	484
550	H4C1	H4 clustered histone 1	6	Highly StudiedExperimental GO Evidence	484