Most Researched

Genes ranked by total PubMed publication count — the most-studied genes in biology.

Filter by chromosome
501550 of 20,598 genesranked by Most Researched
#GeneNameChrTagsPubMed Papers
501TIMP2TIMP metallopeptidase inhibitor 217Highly StudiedExperimental GO Evidence
522
502XRCC3X-ray repair cross complementing 314DNA RepairHomologous Recombination
520
503HDAC6histone deacetylase 6XHighly ConstrainedHub Gene
519
504RASSF1Ras association domain family member 13Tumor SuppressorHighly Studied
519
505PPP2CAprotein phosphatase 2 catalytic subunit alpha5Highly ConstrainedHub Gene
518
506BCL2L11BCL2 like 112Highly StudiedExperimental GO Evidence
517
507IL6Rinterleukin 6 receptor1Hub GeneReceptor
517
508BRD4bromodomain containing 419Highly ConstrainedHub Gene
516
509TUBBtubulin beta class I6Highly ConstrainedHub Gene
516
510GATA3GATA binding protein 310Hub GeneTranscription Factor
515
511IDH2isocitrate dehydrogenase (NADP(+)) 215Hub GeneFDA Approved Target
515
512RXRAretinoid X receptor alpha9Highly ConstrainedHub Gene
515
513IDO1indoleamine 2,3-dioxygenase 18Hub GeneFDA Approved Target
514
514LPAlipoprotein(a)6ProteaseTransporter
514
515BMP4bone morphogenetic protein 414Highly ConstrainedHub Gene
513
516EIF4Eeukaryotic translation initiation factor 4E4Highly ConstrainedHub Gene
513
517MMP7matrix metallopeptidase 711ProteaseFDA Approved Target
513
518CYP1A2cytochrome P450 family 1 subfamily A member 215Hub GeneHighly Studied
511
519MYCNMYCN proto-oncogene, bHLH transcription factor2Highly ConstrainedOncogene
511
520PINK1PTEN induced kinase 11Hub GeneKinase
510
521SRSF1serine and arginine rich splicing factor 117Highly ConstrainedHub Gene
510
522HDAC3histone deacetylase 35Hub GeneFDA Approved Target
509
523NOTCH3notch receptor 319ReceptorClinical Trials
508
524STING1stimulator of interferon response cGAMP interactor 15Ion ChannelTransporter
508
525ANXA1annexin A19Highly StudiedTrending
507
526EWSR1EWS RNA binding protein 122Highly ConstrainedHub Gene
507
527IL15interleukin 154Hub GeneClinical Trials
506
528S100BS100 calcium binding protein B21Highly StudiedExperimental GO Evidence
506
529YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta20Highly ConstrainedHub Gene
505
530BCRBCR activator of RhoGEF and GTPase22KinaseOncogene
502
531TNFSF13BTNF superfamily member 13b13FDA Approved TargetHighly Studied
502
532IGF2BP3insulin like growth factor 2 mRNA binding protein 37Highly ConstrainedTransporter
501
533ITGA5integrin subunit alpha 512Hub GeneReceptor
501
534CFL1cofilin 111Hub GeneHighly Studied
499
535PTBP1polypyrimidine tract binding protein 119Highly ConstrainedHub Gene
499
536VEGFCvascular endothelial growth factor C4Clinical TrialsOMIM Disease Gene
497
537ARID1AAT-rich interaction domain 1A1Highly ConstrainedHub Gene
494
538MC4Rmelanocortin 4 receptor18ReceptorFDA Approved Target
494
539PTX3pentraxin 33Highly StudiedTrending
494
540DNMT3BDNA methyltransferase 3 beta20Hub GeneOMIM Disease Gene
492
541FCGR3AFc gamma receptor IIIa1Hub GeneReceptor
492
542ERGETS transcription factor ERG21Highly ConstrainedOncogene
491
543PRDX1peroxiredoxin 11Highly StudiedTrending
491
544MTR5-methyltetrahydrofolate-homocysteine methyltransferase1Hub GeneOMIM Disease Gene
489
545CATcatalase11OMIM Disease GeneHighly Studied
488
546PTPN1protein tyrosine phosphatase non-receptor type 120Highly ConstrainedHighly Studied
488
547SOCS1suppressor of cytokine signaling 116Hub GeneOMIM Disease Gene
486
548F7coagulation factor VII13ProteaseFDA Approved Target
485
549B2Mbeta-2-microglobulin15Hub GeneOMIM Disease Gene
484
550H4C1H4 clustered histone 16Hub GeneHighly Studied
484