Most Researched

Genes ranked by total PubMed publication count — the most-studied genes in biology.

Filter by chromosome
551600 of 20,598 genesranked by Most Researched
#GeneNameChrTagsPubMed Papers
551CUL3cullin 32TransporterOMIM Disease Gene
481
552TRPV1transient receptor potential cation channel subfamily V member 117Ion ChannelTransporter
481
553GH1growth hormone 117OMIM Disease GeneHighly Studied
480
554WNT5AWnt family member 5A3OMIM Disease GeneHighly Studied
480
555CDK6cyclin dependent kinase 67KinaseFDA Approved Target
479
556CDKN2Bcyclin dependent kinase inhibitor 2B9Tumor SuppressorHighly Studied
479
557IFNB1interferon beta 19Clinical TrialsHighly Studied
479
558IL4Rinterleukin 4 receptor16ReceptorFDA Approved Target
479
559PRMT1protein arginine methyltransferase 119Highly ConstrainedHighly Studied
479
560CANXcalnexin5Highly ConstrainedHighly Studied
478
561HAMPhepcidin antimicrobial peptide19Early PipelineOMIM Disease Gene
477
562KLK3kallikrein related peptidase 319ProteaseFDA Approved Target
477
563LYNLYN proto-oncogene, Src family tyrosine kinase8Highly ConstrainedKinase
475
564PHB1prohibitin 117OncogeneHighly Studied
475
565EPOerythropoietin7OMIM Disease GeneHighly Studied
474
566ITGA2integrin subunit alpha 25ReceptorClinical Trials
473
567SELEselectin E1Clinical TrialsHighly Studied
473
568TTNtitin2KinaseOMIM Disease Gene
472
569FGBfibrinogen beta chain4FDA Approved TargetOMIM Disease Gene
471
570SREBF1sterol regulatory element binding transcription factor 117Transcription FactorOMIM Disease Gene
471
571TET2tet methylcytosine dioxygenase 24Tumor SuppressorOMIM Disease Gene
471
572SMN1survival of motor neuron 1, telomeric5FDA Approved TargetOMIM Disease Gene
470
573APOC3apolipoprotein C311TransporterFDA Approved Target
469
574CD209CD209 molecule19ReceptorHighly Studied
469
575GLI1GLI family zinc finger 112OncogeneOMIM Disease Gene
468
576RARAretinoic acid receptor alpha17Highly ConstrainedOncogene
466
577CTCFCCCTC-binding factor16Highly ConstrainedTranscription Factor
465
578MEFVMEFV innate immunity regulator, pyrin16OMIM Disease GeneHighly Studied
465
579TP53BP1tumor protein p53 binding protein 115DNA RepairHighly Studied
465
580IL12Ainterleukin 12A3FDA Approved TargetHighly Studied
464
581CASP9caspase 91ApoptosisProtease
463
582CDK5cyclin dependent kinase 57KinaseClinical Trials
463
583DNM1Ldynamin 1 like12OMIM Disease GeneHighly Studied
463
584IQGAP1IQ motif containing GTPase activating protein 115Highly StudiedExperimental GO Evidence
463
585PTPN6protein tyrosine phosphatase non-receptor type 612Highly ConstrainedHighly Studied
463
586RPS3ribosomal protein S311DNA RepairHighly Constrained
463
587APOA5apolipoprotein A511TransporterOMIM Disease Gene
462
588FLGfilaggrin1OMIM Disease GeneHighly Studied
461
589VKORC1vitamin K epoxide reductase complex subunit 116FDA Approved TargetOMIM Disease Gene
461
590ACTA1actin alpha 1, skeletal muscle1OMIM Disease GeneHighly Studied
460
591CTNND1catenin delta 111Highly ConstrainedOMIM Disease Gene
459
592HAVCR2hepatitis A virus cellular receptor 25FDA Approved TargetOMIM Disease Gene
459
593AIFM1apoptosis inducing factor mitochondria associated 1XApoptosisHighly Constrained
458
594NEDD4NEDD4 E3 ubiquitin protein ligase15Highly StudiedExperimental GO Evidence
458
595PLCG1phospholipase C gamma 120OMIM Disease GeneHighly Studied
458
596PPP1CAprotein phosphatase 1 catalytic subunit alpha11Highly StudiedExperimental GO Evidence
458
597RUVBL1RuvB like AAA ATPase 13DNA RepairHighly Constrained
458
598ATP2A2ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 212Highly ConstrainedTransporter
455
599EIF4G1eukaryotic translation initiation factor 4 gamma 13Highly ConstrainedOMIM Disease Gene
455
600MTDHmetadherin8Highly StudiedExperimental GO Evidence
455