Most Researched

Genes ranked by total PubMed publication count — the most-studied genes in biology.

Filter by chromosome
Showing 551600 of 20,598 genes
#GeneNameChrTagsPubMedPubMed Papers
551CUL3cullin 32Hub GeneTransporter481481
552TRPV1transient receptor potential cation channel subfamily V member 117Hub GeneIon Channel481481
553GH1growth hormone 117OMIM Disease GeneHighly Studied480480
554WNT5AWnt family member 5A3Hub GeneOMIM Disease Gene480480
555CDK6cyclin dependent kinase 67Hub GeneKinase479479
556CDKN2Bcyclin dependent kinase inhibitor 2B9Tumor SuppressorHighly Studied479479
557IFNB1interferon beta 19Hub GeneClinical Trials479479
558IL4Rinterleukin 4 receptor16Hub GeneReceptor479479
559PRMT1protein arginine methyltransferase 119Highly ConstrainedHub Gene479479
560CANXcalnexin5Highly ConstrainedHub Gene478478
561HAMPhepcidin antimicrobial peptide19Early PipelineOMIM Disease Gene477477
562KLK3kallikrein related peptidase 319ProteaseFDA Approved Target477477
563LYNLYN proto-oncogene, Src family tyrosine kinase8Highly ConstrainedHub Gene475475
564PHB1prohibitin 117OncogeneHighly Studied475475
565EPOerythropoietin7Hub GeneOMIM Disease Gene474474
566ITGA2integrin subunit alpha 25Hub GeneReceptor473473
567SELEselectin E1Clinical TrialsHighly Studied473473
568TTNtitin2Hub GeneKinase472472
569FGBfibrinogen beta chain4FDA Approved TargetOMIM Disease Gene471471
570SREBF1sterol regulatory element binding transcription factor 117Hub GeneTranscription Factor471471
571TET2tet methylcytosine dioxygenase 24Tumor SuppressorOMIM Disease Gene471471
572SMN1survival of motor neuron 1, telomeric5FDA Approved TargetOMIM Disease Gene470470
573APOC3apolipoprotein C311Hub GeneTransporter469469
574CD209CD209 molecule19Hub GeneReceptor469469
575GLI1GLI family zinc finger 112OncogeneTranscription Factor468468
576RARAretinoic acid receptor alpha17Highly ConstrainedHub Gene466466
577CTCFCCCTC-binding factor16Highly ConstrainedHub Gene465465
578MEFVMEFV innate immunity regulator, pyrin16OMIM Disease GeneHighly Studied465465
579TP53BP1tumor protein p53 binding protein 115DNA RepairHub Gene465465
580IL12Ainterleukin 12A3FDA Approved TargetHighly Studied464464
581CASP9caspase 91ApoptosisHub Gene463463
582CDK5cyclin dependent kinase 57Hub GeneKinase463463
583DNM1Ldynamin 1 like12OMIM Disease GeneHighly Studied463463
584IQGAP1IQ motif containing GTPase activating protein 115Hub GeneHighly Studied463463
585PTPN6protein tyrosine phosphatase non-receptor type 612Highly ConstrainedHub Gene463463
586RPS3ribosomal protein S311DNA RepairHighly Constrained463463
587APOA5apolipoprotein A511TransporterOMIM Disease Gene462462
588FLGfilaggrin1OMIM Disease GeneHighly Studied461461
589VKORC1vitamin K epoxide reductase complex subunit 116FDA Approved TargetOMIM Disease Gene461461
590ACTA1actin alpha 1, skeletal muscle1Hub GeneOMIM Disease Gene460460
591CTNND1catenin delta 111Highly ConstrainedHub Gene459459
592HAVCR2hepatitis A virus cellular receptor 25Hub GeneFDA Approved Target459459
593AIFM1apoptosis inducing factor mitochondria associated 1XApoptosisHighly Constrained458458
594NEDD4NEDD4 E3 ubiquitin protein ligase15Hub GeneHighly Studied458458
595PLCG1phospholipase C gamma 120Hub GeneOMIM Disease Gene458458
596PPP1CAprotein phosphatase 1 catalytic subunit alpha11Hub GeneHighly Studied458458
597RUVBL1RuvB like AAA ATPase 13DNA RepairHighly Constrained458458
598ATP2A2ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 212Highly ConstrainedTransporter455455
599EIF4G1eukaryotic translation initiation factor 4 gamma 13Highly ConstrainedHub Gene455455
600MTDHmetadherin8Highly StudiedTrending455455