Most Researched

Genes ranked by total PubMed publication count — the most-studied genes in biology.

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651700 of 20,598 genesranked by Most Researched
#GeneNameChrTagsPubMed Papers
651IGF2BP1insulin like growth factor 2 mRNA binding protein 117Highly ConstrainedTransporter
429
652PGFplacental growth factor14FDA Approved TargetHighly Studied
429
653PPP2R1Aprotein phosphatase 2 scaffold subunit Aalpha19Highly ConstrainedOMIM Disease Gene
429
654CCNT1cyclin T112Highly ConstrainedHighly Studied
428
655HLA-DPB1major histocompatibility complex, class II, DP beta 16Highly StudiedExperimental GO Evidence
428
656HNRNPMheterogeneous nuclear ribonucleoprotein M19Highly StudiedTrending
426
657TCP1t-complex 16Highly ConstrainedOMIM Disease Gene
426
658CD28CD28 molecule2ReceptorClinical Trials
425
659CDC20cell division cycle 201OMIM Disease GeneHighly Studied
425
660SLC3A2solute carrier family 3 member 211ReceptorTransporter
425
661DRD3dopamine receptor D33ReceptorFDA Approved Target
424
662EPHX1epoxide hydrolase 11Highly StudiedExperimental GO Evidence
424
663FGAfibrinogen alpha chain4FDA Approved TargetOMIM Disease Gene
424
664KRT18keratin 1812OMIM Disease GeneHighly Studied
424
665NTRK1neurotrophic receptor tyrosine kinase 11KinaseOncogene
424
666CTSBcathepsin B8ProteaseOMIM Disease Gene
423
667EIF2S1eukaryotic translation initiation factor 2 subunit alpha14Highly ConstrainedHighly Studied
423
668KCNJ11potassium inwardly rectifying channel subfamily J member 1111Ion ChannelTransporter
423
669ADAM10ADAM metallopeptidase domain 1015Highly ConstrainedProtease
422
670METTL3methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit14Highly StudiedTrending
422
671PDIA3protein disulfide isomerase family A member 315Highly StudiedExperimental GO Evidence
422
672SNAI2snail family transcriptional repressor 28Highly ConstrainedOMIM Disease Gene
422
673ADH1Balcohol dehydrogenase 1B (class I), beta polypeptide4FDA Approved TargetHighly Studied
421
674IL22interleukin 2212Clinical TrialsHighly Studied
421
675MAVSmitochondrial antiviral signaling protein20Highly StudiedExperimental GO Evidence
421
676UBE3Aubiquitin protein ligase E3A15Highly ConstrainedOMIM Disease Gene
421
677PAX6paired box 611Highly ConstrainedOMIM Disease Gene
420
678VDAC1voltage dependent anion channel 15ApoptosisTransporter
420
679AMHanti-Mullerian hormone19OMIM Disease GeneHighly Studied
419
680CDH2cadherin 218Highly ConstrainedOMIM Disease Gene
419
681CXCR2C-X-C motif chemokine receptor 22ReceptorClinical Trials
418
682BAP1BRCA1 associated deubiquitinase 13Highly ConstrainedProtease
417
683CASP1caspase 111ProteaseClinical Trials
416
684HNRNPH1heterogeneous nuclear ribonucleoprotein H15OMIM Disease GeneHighly Studied
416
685UBE2L3ubiquitin conjugating enzyme E2 L322Highly ConstrainedHighly Studied
416
686IL21interleukin 214Clinical TrialsOMIM Disease Gene
415
687IL23Rinterleukin 23 receptor1ReceptorOMIM Disease Gene
415
688UCHL1ubiquitin C-terminal hydrolase L14Highly ConstrainedProtease
415
689ACTN4actinin alpha 419Highly ConstrainedTransporter
414
690BST2bone marrow stromal cell antigen 219Highly StudiedTrending
414
691F2Rcoagulation factor II thrombin receptor5ReceptorFDA Approved Target
414
692LTFlactotransferrin3ProteaseTransporter
414
693POSTNperiostin13Highly StudiedTrending
414
694TNFRSF10BTNF receptor superfamily member 10b8ReceptorClinical Trials
414
695ATP5F1AATP synthase F1 subunit alpha18TransporterOMIM Disease Gene
413
696HUWE1HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1XDNA RepairHighly Constrained
413
697ADORA2Aadenosine A2a receptor22ReceptorFDA Approved Target
412
698KLRK1killer cell lectin like receptor K112ReceptorHighly Studied
412
699NGFnerve growth factor1FDA Approved TargetOMIM Disease Gene
412
700PSMC5proteasome 26S subunit, ATPase 517FDA Approved TargetHighly Studied
412