Most Researched

Genes ranked by total PubMed publication count — the most-studied genes in biology.

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1,9011,950 of 20,598 genesranked by Most Researched
#GeneNameChrTagsPubMed Papers
1901SF3A1splicing factor 3a subunit 122Highly ConstrainedExperimental GO Evidence
218
1902SPOPspeckle type BTB/POZ protein17OMIM Disease GeneTrending
218
1903TIMM50translocase of inner mitochondrial membrane 5019TransporterOMIM Disease Gene
218
1904TRRAPtransformation/transcription domain associated protein7Highly ConstrainedKinase
218
1905ALCAMactivated leukocyte cell adhesion molecule3Clinical TrialsExperimental GO Evidence
217
1906CD74CD74 molecule5FDA Approved TargetTrending
217
1907DARS1aspartyl-tRNA synthetase 12OMIM Disease GeneExperimental GO Evidence
217
1908FUBP1far upstream element binding protein 11Highly ConstrainedExperimental GO Evidence
217
1909HK1hexokinase 110KinaseOMIM Disease Gene
217
1910PKP2plakophilin 212OMIM Disease GeneVariant-Rich
217
1911SLIT2slit guidance ligand 24Highly ConstrainedExperimental GO Evidence
217
1912AP2A2adaptor related protein complex 2 subunit alpha 211TransporterExperimental GO Evidence
216
1913APOC1apolipoprotein C119TransporterTrending
216
1914ARHGEF2Rho/Rac guanine nucleotide exchange factor 21Highly ConstrainedOMIM Disease Gene
216
1915AZGP1alpha-2-glycoprotein 1, zinc-binding7Experimental GO EvidenceSwiss-Prot Reviewed
216
1916BCAP31B cell receptor associated protein 31XTransporterOMIM Disease Gene
216
1917CAPN2calpain 21ProteaseTrending
216
1918CCL11C-C motif chemokine ligand 1117Clinical TrialsExperimental GO Evidence
216
1919H1-1H1.1 linker histone, cluster member6Experimental GO EvidenceSwiss-Prot Reviewed
216
1920HSPG2heparan sulfate proteoglycan 21OMIM Disease GeneVariant-Rich
216
1921KLF6KLF transcription factor 610Highly ConstrainedOMIM Disease Gene
216
1922LASP1LIM and SH3 protein 117TransporterExperimental GO Evidence
216
1923MMP12matrix metallopeptidase 1211ProteaseClinical Trials
216
1924RELBRELB proto-oncogene, NF-kB subunit19OMIM Disease GeneExperimental GO Evidence
216
1925TOPBP1DNA topoisomerase II binding protein 13DNA RepairHighly Constrained
216
1926C4Bcomplement C4B (Chido/Rodgers blood group)6OMIM Disease GeneExperimental GO Evidence
215
1927CDC34cell division cycle 34, ubiquitin conjugating enzyme19Experimental GO EvidenceSwiss-Prot Reviewed
215
1928CSDE1cold shock domain containing E11Highly ConstrainedExperimental GO Evidence
215
1929LIG4DNA ligase 413DNA RepairOMIM Disease Gene
215
1930MTNR1Bmelatonin receptor 1B11ReceptorFDA Approved Target
215
1931RIPK3receptor interacting serine/threonine kinase 314KinaseExperimental GO Evidence
215
1932RPL29ribosomal protein L293FDA Approved TargetExperimental GO Evidence
215
1933SELPLGselectin P ligand12ReceptorClinical Trials
215
1934SUPT5HSPT5 homolog, DSIF elongation factor subunit19Highly ConstrainedTrending
215
1935ATP2B1ATPase plasma membrane Ca2+ transporting 112Highly ConstrainedTransporter
214
1936ATP7AATPase copper transporting alphaXHighly ConstrainedTransporter
214
1937DNM1dynamin 19OMIM Disease GeneVariant-Rich
214
1938MOV10Mov10 RNA helicase1Experimental GO EvidenceSwiss-Prot Reviewed
214
1939POLHDNA polymerase eta6DNA RepairOMIM Disease Gene
214
1940RDXradixin11OMIM Disease GeneExperimental GO Evidence
214
1941SETD2SET domain containing 2, histone lysine methyltransferase3DNA RepairHighly Constrained
214
1942SF3B4splicing factor 3b subunit 41Highly ConstrainedOMIM Disease Gene
214
1943STOML2stomatin like 29Experimental GO EvidenceSwiss-Prot Reviewed
214
1944TSPOtranslocator protein22ReceptorTransporter
214
1945EPHB2EPH receptor B21Highly ConstrainedKinase
213
1946FCGR3BFc gamma receptor IIIb1ReceptorExperimental GO Evidence
213
1947GLO1glyoxalase I6Experimental GO EvidenceSwiss-Prot Reviewed
213
1948HLA-DRB3major histocompatibility complex, class II, DR beta 36Experimental GO EvidenceSwiss-Prot Reviewed
213
1949NUP93nucleoporin 9316TransporterOMIM Disease Gene
213
1950OTUB1OTU deubiquitinase, ubiquitin aldehyde binding 111DNA RepairProtease
213