Most Researched

Genes ranked by total PubMed publication count — the most-studied genes in biology.

Filter by chromosome
Showing 1,9512,000 of 20,598 genes
#GeneNameChrTagsPubMedPubMed Papers
1951PADI4peptidyl arginine deiminase 41Transcription FactorOMIM Disease Gene
213
213
1952RELREL proto-oncogene, NF-kB subunit2OncogeneTranscription Factor
213
213
1953RFC3replication factor C subunit 313DNA RepairHub Gene
213
213
1954RRM2ribonucleotide reductase regulatory subunit M22DNA RepairHighly Constrained
213
213
1955SPRY2sprouty RTK signaling antagonist 213OMIM Disease GeneTrending
213
213
1956THRAthyroid hormone receptor alpha17ReceptorTranscription Factor
213
213
1957COL7A1collagen type VII alpha 1 chain3FDA Approved TargetOMIM Disease Gene
212
212
1958DSTdystonin6Highly ConstrainedOMIM Disease Gene
212
212
1959FHfumarate hydratase1DNA RepairHub Gene
212
212
1960GAAalpha glucosidase17FDA Approved TargetOMIM Disease Gene
212
212
1961GADD45Agrowth arrest and DNA damage inducible alpha1TrendingExperimental GO Evidence
212
212
1962HLA-DRB5major histocompatibility complex, class II, DR beta 56Clinical TrialsTrending
212
212
1963MAOBmonoamine oxidase BXHub GeneFDA Approved Target
212
212
1964MAP2K4mitogen-activated protein kinase kinase 417Highly ConstrainedKinase
212
212
1965PAX5paired box 59OncogeneTranscription Factor
212
212
1966RIPK2receptor interacting serine/threonine kinase 28ApoptosisKinase
212
212
1967RPS15ribosomal protein S1519Hub GeneFDA Approved Target
212
212
1968SART3spliceosome associated factor 3, U4/U6 recycling protein12TrendingExperimental GO Evidence
212
212
1969SLC25A11solute carrier family 25 member 1117TransporterOMIM Disease Gene
212
212
1970SMURF2SMAD specific E3 ubiquitin protein ligase 217TrendingExperimental GO Evidence
212
212
1971TUBB6tubulin beta 6 class V18FDA Approved TargetOMIM Disease Gene
212
212
1972UBR4ubiquitin protein ligase E3 component n-recognin 41Highly ConstrainedOMIM Disease Gene
212
212
1973APOBEC3Fapolipoprotein B mRNA editing enzyme catalytic subunit 3F22Experimental GO EvidenceSwiss-Prot Reviewed
211
211
1974CHD7chromodomain helicase DNA binding protein 78Highly ConstrainedTranscription Factor
211
211
1975FAF2Fas associated factor family member 25Highly ConstrainedTrending
211
211
1976FANCIFA complementation group I15DNA RepairHub Gene
211
211
1977HBEGFheparin binding EGF like growth factor5ReceptorEarly Pipeline
211
211
1978MTREXMtr4 exosome RNA helicase5Hub GeneExperimental GO Evidence
211
211
1979PFKFB36-phosphofructo-2-kinase/fructose-2,6-biphosphatase 310KinaseTrending
211
211
1980PNNpinin, desmosome associated protein14Transcription FactorTumor Suppressor
211
211
1981PSMB3proteasome 20S subunit beta 317Hub GeneFDA Approved Target
211
211
1982SEC61A1SEC61 translocon subunit alpha 13Hub GeneTransporter
211
211
1983TGthyroglobulin8OMIM Disease GeneTrending
211
211
1984AKR1C3aldo-keto reductase family 1 member C310Hub GeneTrending
210
210
1985CCR6C-C motif chemokine receptor 66Hub GeneReceptor
210
210
1986H2AC20H2A clustered histone 201Hub GeneExperimental GO Evidence
210
210
1987HSD17B4hydroxysteroid 17-beta dehydrogenase 45OMIM Disease GeneVariant-Rich
210
210
1988LARS1leucyl-tRNA synthetase 15OMIM Disease GeneTrending
210
210
1989PLD1phospholipase D13Hub GeneOMIM Disease Gene
210
210
1990PRDM1PR/SET domain 16Highly ConstrainedTranscription Factor
210
210
1991RALYRALY heterogeneous nuclear ribonucleoprotein20Transcription FactorTrending
210
210
1992USP8ubiquitin specific peptidase 815Highly ConstrainedProtease
210
210
1993ACIN1apoptotic chromatin condensation inducer 114Highly ConstrainedTrending
209
209
1994AIPAHR interacting HSP90 co-chaperone11OMIM Disease GeneTrending
209
209
1995CCR3C-C motif chemokine receptor 33Hub GeneReceptor
209
209
1996HTRA2HtrA serine peptidase 22ProteaseOMIM Disease Gene
209
209
1997IFNAR1interferon alpha and beta receptor subunit 121Hub GeneReceptor
209
209
1998LATS2large tumor suppressor kinase 213KinaseTumor Suppressor
209
209
1999LIMA1LIM domain and actin binding 112TrendingExperimental GO Evidence
209
209
2000LONP1lon peptidase 1, mitochondrial19ProteaseOMIM Disease Gene
209
209