Most Researched

Genes ranked by total PubMed publication count — the most-studied genes in biology.

Filter by chromosome
1,1511,200 of 20,598 genesranked by Most Researched
#GeneNameChrTagsPubMed Papers
1151F9coagulation factor IXXHighly ConstrainedProtease
302
1152IGFBP2insulin like growth factor binding protein 22TrendingExperimental GO Evidence
302
1153OPTNoptineurin10OMIM Disease GeneTrending
302
1154RPS7ribosomal protein S72Highly ConstrainedFDA Approved Target
302
1155STAU1staufen double-stranded RNA binding protein 120Highly ConstrainedTrending
302
1156CXCL1C-X-C motif chemokine ligand 14TrendingExperimental GO Evidence
301
1157DKC1dyskerin pseudouridine synthase 1XHighly ConstrainedOMIM Disease Gene
301
1158HNRNPA3heterogeneous nuclear ribonucleoprotein A32TrendingExperimental GO Evidence
301
1159NPPAnatriuretic peptide A1OMIM Disease GeneExperimental GO Evidence
301
1160PIM1Pim-1 proto-oncogene, serine/threonine kinase6KinaseOncogene
301
1161RYR2ryanodine receptor 21Ion ChannelReceptor
301
1162SUMO2small ubiquitin like modifier 217TrendingExperimental GO Evidence
301
1163ALPLalkaline phosphatase, biomineralization associated1OMIM Disease GeneVariant-Rich
300
1164DCTN1dynactin subunit 12TransporterOMIM Disease Gene
300
1165GLAgalactosidase alphaXHighly ConstrainedFDA Approved Target
300
1166GNB1G protein subunit beta 11Highly ConstrainedOMIM Disease Gene
300
1167IRS2insulin receptor substrate 213Experimental GO EvidenceSwiss-Prot Reviewed
300
1168PPP1CBprotein phosphatase 1 catalytic subunit beta2Highly ConstrainedOMIM Disease Gene
300
1169PRDX6peroxiredoxin 61TrendingExperimental GO Evidence
300
1170CCL3C-C motif chemokine ligand 317KinaseExperimental GO Evidence
299
1171NHERF1NHERF family PDZ scaffold protein 117OMIM Disease GeneExperimental GO Evidence
299
1172RPL13ribosomal protein L1316Highly ConstrainedFDA Approved Target
299
1173SMN2survival of motor neuron 2, centromeric5FDA Approved TargetSwiss-Prot Reviewed
299
1174CADcarbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase2OMIM Disease GeneVariant-Rich
298
1175CEACAM5CEA cell adhesion molecule 519OncogeneFDA Approved Target
298
1176CGAScyclic GMP-AMP synthase6DNA RepairExperimental GO Evidence
298
1177KHSRPKH-type splicing regulatory protein19Highly ConstrainedTransporter
298
1178MCM5minichromosome maintenance complex component 522OMIM Disease GeneExperimental GO Evidence
298
1179SF3B2splicing factor 3b subunit 211Highly ConstrainedOMIM Disease Gene
298
1180SMC3structural maintenance of chromosomes 310DNA RepairHighly Constrained
298
1181SOS1SOS Ras/Rac guanine nucleotide exchange factor 12Highly ConstrainedOMIM Disease Gene
298
1182TCF3transcription factor 319OncogeneTranscription Factor
298
1183RPA2replication protein A21DNA RepairHomologous Recombination
297
1184RPS18ribosomal protein S186Highly ConstrainedExperimental GO Evidence
297
1185THRBthyroid hormone receptor beta3ReceptorFDA Approved Target
297
1186ABCC8ATP binding cassette subfamily C member 811ReceptorTransporter
296
1187CRHR1corticotropin releasing hormone receptor 117ReceptorFDA Approved Target
296
1188GRIN1glutamate ionotropic receptor NMDA type subunit 19Ion ChannelReceptor
296
1189RPL14ribosomal protein L143FDA Approved TargetExperimental GO Evidence
296
1190RPS14ribosomal protein S145Highly ConstrainedFDA Approved Target
296
1191RPS9ribosomal protein S919Highly ConstrainedFDA Approved Target
296
1192RPTORregulatory associated protein of MTOR complex 117Highly ConstrainedClinical Trials
296
1193TFAP2Atranscription factor AP-2 alpha6Highly ConstrainedOMIM Disease Gene
296
1194TXNIPthioredoxin interacting protein1Tumor SuppressorTrending
296
1195U2AF1U2 small nuclear RNA auxiliary factor 121OMIM Disease GeneExperimental GO Evidence
296
1196ACLYATP citrate lyase17FDA Approved TargetExperimental GO Evidence
295
1197ALYREFAly/REF export factor17Highly ConstrainedTransporter
295
1198CUL2cullin 210Highly ConstrainedExperimental GO Evidence
295
1199DIABLOdiablo IAP-binding mitochondrial protein12OMIM Disease GeneExperimental GO Evidence
295
1200HTR2C5-hydroxytryptamine receptor 2CXReceptorFDA Approved Target
295