Most Researched

Genes ranked by total PubMed publication count — the most-studied genes in biology.

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1,4011,450 of 20,598 genesranked by Most Researched
#GeneNameChrTagsPubMed Papers
1401PDIA6protein disulfide isomerase family A member 62Experimental GO EvidenceSwiss-Prot Reviewed
267
1402PIK3C3phosphatidylinositol 3-kinase catalytic subunit type 318KinaseExperimental GO Evidence
267
1403POLR2ERNA polymerase II, I and III subunit E19Experimental GO EvidenceSwiss-Prot Reviewed
267
1404RPL13Aribosomal protein L13a19Highly ConstrainedFDA Approved Target
267
1405RPL15ribosomal protein L153Highly ConstrainedFDA Approved Target
267
1406RPS25ribosomal protein S2511FDA Approved TargetExperimental GO Evidence
267
1407SERPINB5serpin family B member 518Experimental GO EvidenceSwiss-Prot Reviewed
267
1408SNRPD1small nuclear ribonucleoprotein D1 polypeptide18Experimental GO EvidenceSwiss-Prot Reviewed
267
1409CASP7caspase 710ApoptosisProtease
266
1410DDX39BDExD-box helicase 39B6Highly ConstrainedTransporter
266
1411FGFR4fibroblast growth factor receptor 45KinaseReceptor
266
1412G3BP2G3BP stress granule assembly factor 24TransporterTrending
266
1413MAXMYC associated transcriptional regulator X14Highly ConstrainedTranscription Factor
266
1414PIEZO1piezo type mechanosensitive ion channel component 1 (Er blood group)16Ion ChannelTransporter
266
1415TNPO1transportin 15Highly ConstrainedTransporter
266
1416VAPBVAMP associated protein B and C20OMIM Disease GeneTrending
266
1417VPS35VPS35 retromer complex component16Highly ConstrainedTransporter
266
1418HPRT1hypoxanthine phosphoribosyltransferase 1XOMIM Disease GeneVariant-Rich
265
1419ITPR1inositol 1,4,5-trisphosphate receptor type 13Highly ConstrainedIon Channel
265
1420RICTORRPTOR independent companion of MTOR complex 25Highly ConstrainedExperimental GO Evidence
265
1421RPL28ribosomal protein L2819FDA Approved TargetExperimental GO Evidence
265
1422CD247CD247 molecule1ReceptorOMIM Disease Gene
264
1423ERAP1endoplasmic reticulum aminopeptidase 15ProteaseClinical Trials
264
1424MACROH2A1macroH2A.1 histone5DNA RepairHighly Constrained
264
1425MAP4microtubule associated protein 43Experimental GO EvidenceSwiss-Prot Reviewed
264
1426RPS15Aribosomal protein S15a16FDA Approved TargetOMIM Disease Gene
264
1427SCRIBscribble planar cell polarity protein8OMIM Disease GeneExperimental GO Evidence
264
1428TREM1triggering receptor expressed on myeloid cells 16ReceptorClinical Trials
264
1429CCND2cyclin D212OMIM Disease GeneExperimental GO Evidence
263
1430COL4A1collagen type IV alpha 1 chain13Highly ConstrainedFDA Approved Target
263
1431CPSF6cleavage and polyadenylation specific factor 612Highly ConstrainedTrending
263
1432DNAJA2DnaJ heat shock protein family (Hsp40) member A216Highly ConstrainedExperimental GO Evidence
263
1433DYNLL1dynein light chain LC8-type 112TransporterExperimental GO Evidence
263
1434H4C16H4 histone 1612OMIM Disease GeneSwiss-Prot Reviewed
263
1435KITLGKIT ligand12OMIM Disease GeneExperimental GO Evidence
263
1436NAT10N-acetyltransferase 1011TrendingExperimental GO Evidence
263
1437SNRPD2small nuclear ribonucleoprotein D2 polypeptide19Experimental GO EvidenceSwiss-Prot Reviewed
263
1438WFS1wolframin ER transmembrane glycoprotein4OMIM Disease GeneTrending
263
1439COPB1coat protein complex I subunit beta 111Highly ConstrainedTransporter
262
1440DUSP1dual specificity phosphatase 15TrendingExperimental GO Evidence
262
1441FGF1fibroblast growth factor 15FDA Approved TargetExperimental GO Evidence
262
1442NFATC2nuclear factor of activated T cells 220OMIM Disease GeneTrending
262
1443PORcytochrome p450 oxidoreductase7OMIM Disease GeneVariant-Rich
262
1444SCDstearoyl-CoA desaturase10Highly ConstrainedExperimental GO Evidence
262
1445SREBF2sterol regulatory element binding transcription factor 222TrendingExperimental GO Evidence
262
1446SSBP1single stranded DNA binding protein 17OMIM Disease GeneExperimental GO Evidence
262
1447ACACAacetyl-CoA carboxylase alpha17OMIM Disease GeneExperimental GO Evidence
261
1448EDNRBendothelin receptor type B13ReceptorFDA Approved Target
261
1449HNRNPUL1heterogeneous nuclear ribonucleoprotein U like 119Highly ConstrainedExperimental GO Evidence
261
1450PDPNpodoplanin1Experimental GO EvidenceSwiss-Prot Reviewed
261